Publication for PSME2 and STAT1
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | PSME2 | proteasome activator subunit 2 | 5721 | [link] | ||
| hsa | STAT1 | signal transducer and activator of transcription 1 | 6772 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 25329145 | 0.97 | STAT1, HLA-C, PSME1/PA28a, PSME2/PA28b, WARS, HSPA1L/HSP70T, EPX, LAP3) |
| 31015447 | 0.96 | STAT1, PML, OAS2, OAS3, MX1, ADAR, ISG15, IFI35, IFIT3, IFI27, PSMB8, PSMB9, BST2, IRF1, IRF9, CD74, PSME1, PSME2, HLA-DQA1/DPA1/ DPB1/DRA/ DQB2/DRB1/ DQB1/DMA/DMB/DOA, HLA-A/B/C/E/F) and include the inhibitory receptor LAG3. |
| 28174229 | 0.95 | PSME2, PSMB8, PSMB9, SAMDH1, SOD2, STAT1, STAT2, and WARS. |
| 29900059 | 0.95 | STAT1) and the HLA class I enhanceosome (NLRC5, CIITA, IRF1, RFX5, RFXANK, RFXAP, X2BP, NF-Y) that mediate the transcriptional activation of HLA class I genes; PSME1, PSME2, PSME3 genes coding for the alpha, beta, and gamma subunits that make up the proteasome activator complex PA28 for peptide generation; ERAP1 and ERAP2 that trim longer precursor of antigenic peptides; HSPA and HSPC that chaperones the peptides to their loading on the MHC class I in the endoplasmic reticulum; and TAP1, TAP2, TAPBP, calreticulin, calnexin, PDIA3, beta2-microglobulin and HLA class I genes that participate in the formation of the MHC class I peptide complex. |
| 27434509 | 0.91 | STAT1 clearly colocalized with the proteasomal marker PA28beta in the nucleus (S3 Fig). |
| 24563857 | 0.89 | STAT-1 proteins and interferon regulatory factor-1 (IRF-1) bind to the interferon gamma activated site (GAS), a short stretch of DNA, that functions as the promotor of IFN-gamma-activated genes, in this case the interferon-stimulated response element (ISRE), that expresses (amongst others) the inducible proteasomal subunits (beta1i, beta2i and beta5i), that are incorporated into de novo synthesized 20S proteasomes, and the Pa28alpha- and Pa28beta-subunits of the 11S regulator. |
| 21173013 | 0.88 | PSME2 and transcripts involved in interferon (IFN) signalling (SOCS1, STAT1 and STAT2). |
| 23095257 | 0.61 | STAT1, STAT3, TAP1, PSME2, and PSMB8), and in UC vs. normal conditions (mainly HNF4G, KLF5, AQP8, ATP2B1, and SLC16A). |
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