Publication for PSME2 and STAT1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa PSME2 proteasome activator subunit 2 5721 [link]
hsa STAT1 signal transducer and activator of transcription 1 6772

Pubmed ID Priority Text
25329145 0.97 STAT1, HLA-C, PSME1/PA28a, PSME2/PA28b, WARS, HSPA1L/HSP70T, EPX, LAP3)
31015447 0.96 STAT1, PML, OAS2, OAS3, MX1, ADAR, ISG15, IFI35, IFIT3, IFI27, PSMB8, PSMB9, BST2, IRF1, IRF9, CD74, PSME1, PSME2, HLA-DQA1/DPA1/ DPB1/DRA/ DQB2/DRB1/ DQB1/DMA/DMB/DOA, HLA-A/B/C/E/F) and include the inhibitory receptor LAG3.
28174229 0.95 PSME2, PSMB8, PSMB9, SAMDH1, SOD2, STAT1, STAT2, and WARS.
29900059 0.95 STAT1) and the HLA class I enhanceosome (NLRC5, CIITA, IRF1, RFX5, RFXANK, RFXAP, X2BP, NF-Y) that mediate the transcriptional activation of HLA class I genes; PSME1, PSME2, PSME3 genes coding for the alpha, beta, and gamma subunits that make up the proteasome activator complex PA28 for peptide generation; ERAP1 and ERAP2 that trim longer precursor of antigenic peptides; HSPA and HSPC that chaperones the peptides to their loading on the MHC class I in the endoplasmic reticulum; and TAP1, TAP2, TAPBP, calreticulin, calnexin, PDIA3, beta2-microglobulin and HLA class I genes that participate in the formation of the MHC class I peptide complex.
27434509 0.91 STAT1 clearly colocalized with the proteasomal marker PA28beta in the nucleus (S3 Fig).
24563857 0.89 STAT-1 proteins and interferon regulatory factor-1 (IRF-1) bind to the interferon gamma activated site (GAS), a short stretch of DNA, that functions as the promotor of IFN-gamma-activated genes, in this case the interferon-stimulated response element (ISRE), that expresses (amongst others) the inducible proteasomal subunits (beta1i, beta2i and beta5i), that are incorporated into de novo synthesized 20S proteasomes, and the Pa28alpha- and Pa28beta-subunits of the 11S regulator.
21173013 0.88 PSME2 and transcripts involved in interferon (IFN) signalling (SOCS1, STAT1 and STAT2).
23095257 0.61 STAT1, STAT3, TAP1, PSME2, and PSMB8), and in UC vs. normal conditions (mainly HNF4G, KLF5, AQP8, ATP2B1, and SLC16A).



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