Publication for STAT1 and DDX60

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa STAT1 signal transducer and activator of transcription 1 6772 [link]
hsa DDX60 DExD/H-box helicase 60 55601

Pubmed ID Priority Text
27871313 0.97 STAT1, ISG15, OAS1, OAS2, OAS3, IFI35, IFI44, IFI6, IFIH1, IFIT3, IFIT5, HERC5, HERC6, DDX58, DDX60).
0.96 STAT1, IRF7, IRF9, STAT1, ISG15, OAS1, OAS2, OAS3, IFI35, IFI44, IFI6, IFIH1, IFIT3, IFIT5, HERC5, HERC6, DDX58, and DDX60).
27401546 0.97 DDX60, PLSCR1, ISG12, IFITM3 and IFI44L) and 3 ISGs required IQGAP2 and RelA for their full induction by IFN (IFI6, OAS1 and IFIT1), probably resulting from a secondary response as the induction of transcription factors such as STAT1 and IRF2 were found to depend on IQGAP2 and RelA. Taken together, these data indicate that the IQGAP2-RelA pathway of IFN is necessary for the full induction of the anti-HCV ISG arsenal.
28977426 0.96 DDX60, IFI16, MDA5, RIG-I, LGP2, STAT1, IRF1, IRF7, IRF9, OASL and OAS2.
0.89 DDX60, MDA5/IFIH1, RIG-I/DDX58, LGP2, PKR, OAS1/IFI4, OAS2, OASL, IRF1, IRF7, IRF9, IFNB, STAT1 (in green).
30717477 0.93 DDX60, IFI27, IFIT1, IFITM1, IRF7, ISG15, LY6E, melanoma Differentiation-Associated protein 5 (MDA5), MX1, Nicotinamide phosphoribosyltransferase (NAMPT), OASL, PML, RTP4, and STAT1).
24260178 0.92 STAT1-57 genes, there was strong overrepresentation of genes involved in response to virus (e.g., DDX58, DDX60, EIF2AK2, HERC5, IFI35, IFI44, IFI44L, IFIT1, IFITM1, IRF9, ISG15, MX1, MX2, OAS2, OAS3, PLSCR1, STAT1 and TRIM22; P = 8.4x10-16).
25264520 0.92 Ddx60 and Ifih1 (also known as MDA-5) were mostly unchanged, while the interferon-induced genes Stat1, Ifit1 and Ifitm3 were significantly increased in cells pre-treated with Th2 cytokines.
29301323 0.62 STAT1, DDX60, HERC6, IFI27, PLSCR1, IFIT1, IFI35, IFIT3; c:ISG15; d:ERP70.
26695443 0.61 DDX60, IFI44, IFI44L, IFI6, IFIT1, IFIT3, IFITM1, IRF9, MX1, OAS1, OAS2, PARP12, PARP9, SAMD9, STAT1, STAT2, UBE2L6, ZNFX1) at D7 and D14.



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