Publication for SPRR1B and SPRR4

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	SPRR1B	small proline rich protein 1B	6699			[link]
hsa	SPRR4	small proline rich protein 4	163778

Pubmed ID	Priority	Text
28119736	0.97	SPRR4 in its cornifin domain showed significant variation in dN/dS across 14 mammals, this same site was not detected in the primate clade test (M1a-M2a) indicating that different sites in SPRR4 were under positive selection in primates vs. mammals.
	0.97	cornifin domains of SPRR1A and SPRR4 suggest modulation of cornified envelope scaffold with an anticipated effect on skin barrier function.
	0.96	cornifin domains of SPRR1A and SPRR4, respectively.
	0.94	SPRR4's cornifin domain across the mammalian lineage.
	0.94	SPRR4 with positive selection of codon 60 site in the conserved cornifin domain across mammals in contrast to non-cornifin domain in codons 26, 39, 43, 70, and 78 that were selected in the primate lineage.
	0.76	cornifin domain suggesting ongoing molecular evolution for SPRR4.
25482884	0.97	SPRR1B, SPRR2A, SPRR2B, SPRR2D, SPRR2F, SPRR3, SPRR4, LCE1A, LCE1B, LCE3D, LCE3E, S100A7, S100A15, trichohyalin-like 1 protein, hornerin, loricrin and involucrin (Fig. 6).