Publication for SFPQ and CPSF6

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	SFPQ	splicing factor proline and glutamine rich	6421			[link]
hsa	CPSF6	cleavage and polyadenylation specific factor 6	11052

Pubmed ID	Priority	Text
28673861	0.98	CPSF6 and SFPQ show co-expression in the breast cancer cases present in the TMAs used (Supplementary Fig. S3A (left panel)).
	0.97	CPSF6 and Nudt21 with paraspeckles proteins (SFPQ, PSPC1 and P54nrb) by co-immunoprecipitation experiments.
	0.95	CPSF6 and SFPQ expression in TMA (BC081120) containing 100 IDC and 10 normal adjacent tissues.
	0.95	CPSF6 positive breast cancer cases were also positive for SFPQ, whereas, only 11/38 (28.9%) of SFPQ positive cases in CPSF6 negative group (p = 4.1E-06) (Fig. 4I).
	0.95	CPSF6 to physically interact with paraspeckles core proteins SFPQ and PSPC1 but not with p54nrb (Fig. 5A-C).
20421926	0.96	Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) and the Splicing factor proline/glutamine-rich (SFPQ), was higher in Snail1-expressing cells than in controls.
	0.96	SFPQ and CPSF6 are involved in pre-mRNA processing and localized in nuclear paraspeckles, which suggests a possible coordinated effect of Snail1.
	0.95	CPSF6 and SFPQ proteins involved in RNA polyadenylation and splicing, respectively.
	0.90	CPSF6 and SFPQ are fusion partners for tyrosine kinases in haematological malignancies.
	0.85	CPSF6, HNRNPH3 and SFPQ) and intracellular signaling (PI3KR1, RANBP1 and 14-3-3 protein family).
24173718	0.96	CPSF6, and SFPQ are contained within the MG132-induced elongated paraspeckles.
	0.94	CPSF6, and SFPQ in control and MG132-amplified paraspeckles was determined by I-EM.
	0.86	CPSF6, and SFPQ were similarly distributed and similarly abundant within the paraspeckles of control (dimethyl sulfoxide [DMSO]) and MG132-treated HeLa cells (illustrated in Figure 2D and quantified in Figure 2E).
30087896	0.96	SFPQ [splicing factor, proline- and glutamine-rich (also known as PSF (PTB-associated splicing factor)], RNA binding motif (RBM) 14, and CPSF6 (cleavage and polyadenylation specific factor 6) [Reviewed in (Yamazaki and Hirose,)].
	0.93	SFPQ, CPSF6, EWS, FUS, TAF15, DAZAP1, RBM3, SS18L1, WT1, BCL6, BCL11A, ZNF4444, and HNRNPH1 are implicated in various types of cancer (reviewed in Yamazaki and Hirose,).
22476590	0.95	PSF and CFIm68 were demonstrated to localize to the IGAZ, suggesting that this structure is essentially equivalent to paraspeckles.
25779042	0.93	CFIm subunit PCF11 and several splicing factors, including PRP40, CA150 and PSF.
28484853	0.92	SFPQ, and CPSF6 corresponding with 50% depletion of nucleoplasmic SFPQ and NONO pools.
27783096	0.77	SFPQ (splicing factor, proline- and glutamine-rich), CPSF6, and RNA-binding motif 14 (RBM14), and dozens of new paraspeckle proteins have recently been identified.
30355755	0.66	PSF (polypyrimidine tract-binding protein-associated splicing factor, gene symbol: SFPQ) and CFIm68 (mammalian cleavage factor I, gene symbol: CPSF6), large-scale localization screening using fluorescently tagged proteins further identified 37 proteins that exhibit substantial enrichment in paraspeckles, all of which contain domains with RNA-binding properties.