Publication for RAD51 and CLSPN

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	RAD51	RAD51 recombinase	5888			[link]
hsa	CLSPN	claspin	63967

Pubmed ID	Priority	Text
23552402	0.98	RAD51 (P=0.007), CYCLIN A (P=0.0128), CDC25A (P=0.0196), CLASPIN (P=0.0233), CDC6 (P=0.0404), POLL (P=0.0464) and RPA (P=0.0458).
	0.98	RAD51, CLASPIN and CDC6 was associated with overall, disease-free and relapse-free survival (Table 3).
	0.98	RAD51, CLASPIN or CDC6.
	0.98	CLASPIN, RAD51 and CDC6 genes on the resistance to replication stress.
	0.97	RAD51, CLASPIN and CDC6 separates patients into low- and high-risk groups, with a hazard ratio of 14.3 (95% CI 5.1-40.3, P<0.001).
	0.97	CLASPIN and RAD51, behave as a single 'metamarker' (Supplementary Figure S2B).
	0.97	RAD51, CLASPIN or CDC6 did not correlate (P>0.05, Supplementary Table S3) with the therapeutic strategy or with the number of metastasis-containing nodes.
	0.97	RAD51, CLASPIN and CDC6 genes, either considered individually or as a signature, is associated with a bad prognosis in NSCLC.
	0.96	RAD51, CYCLIN A, CDC25A, CLASPIN and CDC6 (Supplementary Table S2).
	0.93	RAD51, CLASPIN and POLQ genes promotes cancer progression by increasing resistance to endogenous replication stress in a concerted manner.
	0.92	CLASPIN and CDC6), except RAD51 (Table 4), presumably because RAD51 expression correlates with that of PCNA and KI67 (Pearson's coefficients rho=0.54 and rho=0.81, respectively).
	0.89	CLASPIN and RAD51 would favor the maintenance and the recovery of stalled replication forks.
	0.75	Claspin and Rad51 are two other key players of the replication stress response, which promote the maintenance and recovery of arrested forks, respectively.
23776525	0.98	RAD51, CDC6, CLSPN; Fig. 1A).
	0.98	CLSPN , TIPIN ), regulation of base-excision repair (BRCA1 ), and new DNA synthesis during homologous recombination repair (CDC45L , GINS1 , MCM10 ; Table S4), in addition to those already found to be involved in homologous recombination (e.g. RAD51, MSH2, BLM; Table S1 and Fig. 1C).
20373286	0.98	Claspin regulation, resulting in inhibition of RAD51 function and decreased HR (Fig 7).
26010955	0.98	RAD51, Claspin, FANC proteins and BLM, are necessary for CFS maintenance.
26872382	0.98	Claspin and Mre11/Rad51.
30424570	0.98	Claspin, breast cancer type 2 susceptibility protein (BRCA2), and Rad51, slows replication forks and also increases the number of initiation events, at least in studies where initiation events were examined.
30498558	0.97	claspin and Rad51 wanes over the 24 hours after UV irradiation, specifically in the high glucose condition (A).
	0.95	claspin, Rad51, Mre11, gammaH2AX).
	0.94	claspin and Rad51 proteins after low dose UV irradiation, however, was not sustained in the HG condition.
	0.91	claspin, Rad51, Mre11, and gammaH2AX, were analyzed.
28721269	0.97	claspin (CLSPN), and CHEK2, which together with breast cancer 2 early onset (BRCA2), RAD51 recombinase (RAD51), its enhancer RAD51AP1 (RAD51AP1), and MMS22-like DNA repair protein (MMS22L) promote genome stability.
	0.97	CLSPN: claspin; BRCA2: breast cancer 2, early onset; RAD51: RAD51 recombinase; RAD51AP1: RAD51 associated protein 1; MMS22L: MMS22-like, DNA repair protein; TONSL: tonsoku-like, DNA repair protein.
32178478	0.97	claspin (CLSPN), RAD51 recombinase (RAD51), ataxia telangiectasia and Rad3-related protein (ATR), topoisomerase II binding protein 1 (TOPBP1), minichromosome maintenance complex component 4 (MCM4), and cell division cycle 45 (CDC45).
	0.74	claspin (CLSPN), RAD51recombinase (RAD51), ATR, topoisomerase (DNA) II binding protein 1 (TOPBP1), minichromosome maintenance complex component 4 (MCM4), and cell division cycle 45 (CDC45).
29606576	0.97	claspin-CHK1 complex to activate the G2 cell-cycle checkpoint for DNA damage, an endonuclease complex containing CtIP that resects double-stranded DNA dsDNA) to generate overhanging ssDNA substrates, and a DNA recombination complex containing the recombinase RAD51 to localize it to sites of DNA breakage.
32076484	0.97	CLSPN, CHEK1, CDC25A, WEE1, CKS2) and DDR (BRCA2, RAD51).
25025768	0.96	Claspin, a protein implicated in DNA checkpoint activation, also led to significant reduction of the RAD51 foci, further suggesting the requirement of checkpoint proteins in inducing a persistent DNA damage response.
30854428	0.72	Rad51 and Claspin, to facilitate a homologous recombinant or adaptation of DNA checkpoint arrest.