Publication for POLQ and CLSPN
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | POLQ | DNA polymerase theta | 10721 | [link] | ||
| hsa | CLSPN | claspin | 63967 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 23552402 | 0.98 | POLQ (95%CI 2.6-517.4, P=0.008), 23.5 for PLK1 (95%CI 1.9-288.4, P=0.01), 20.7 for CLASPIN (95%CI 1.5-275.9, P=0.02) and 18.5 for CDC6 (95%CI 1.3-267.4, P=0.03). |
| 0.98 | POLQ, PLK1, RAD51, CLASPIN and CDC6 separates patients into low- and high-risk groups, with a hazard ratio of 14.3 (95% CI 5.1-40.3, P<0.001). | |
| 0.98 | POLQ, PLK1, RAD51, CLASPIN or CDC6 did not correlate (P>0.05, Supplementary Table S3) with the therapeutic strategy or with the number of metastasis-containing nodes. | |
| 0.98 | CLASPIN and POLQ genes promotes cancer progression by increasing resistance to endogenous replication stress in a concerted manner. | |
| 0.97 | POLQ, CLASPIN and CHK1 (T/N>3), CDC45, CDC6, KI67, HMGA2 and CDT1 (T/N>4) and PLK1 (T/N>5). | |
| 0.96 | POLQ, CDC6 and PLK1, and to a lesser extent CLASPIN and RAD51, behave as a single 'metamarker' (Supplementary Figure S2B). | |
| 0.96 | POLQ, PLK1, RAD51, CLASPIN and CDC6 genes, either considered individually or as a signature, is associated with a bad prognosis in NSCLC. | |
| 0.95 | POLQ, PLK1, RAD51, CYCLIN A, CDC25A, CLASPIN and CDC6 (Supplementary Table S2). | |
| 0.95 | POLQ, PLK1, RAD51, CLASPIN and CDC6 was associated with overall, disease-free and relapse-free survival (Table 3). | |
| 0.94 | POLQ, PLK1, RAD51, CLASPIN and CDC6 was associated with overall, disease-free and relapse-free survival. | |
| 0.92 | POLQ, PLK1, RAD51, CLASPIN or CDC6. | |
| 0.89 | POLQ, PLK1, CLASPIN, RAD51 and CDC6 genes on the resistance to replication stress. | |
| 0.82 | POLQ, PLK1, CLASPIN and CDC6), except RAD51 (Table 4), presumably because RAD51 expression correlates with that of PCNA and KI67 (Pearson's coefficients rho=0.54 and rho=0.81, respectively). | |
| 0.72 | POLQ (P=0.0008), PLK1 (P=0.0062), RAD51 (P=0.007), CYCLIN A (P=0.0128), CDC25A (P=0.0196), CLASPIN (P=0.0233), CDC6 (P=0.0404), POLL (P=0.0464) and RPA (P=0.0458). | |
| 32104698 | 0.83 | CLSPN, E2F2, and POLQ (Figure 4(b)). |
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