Publication for WDR35 and DYNC2H1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa WDR35 WD repeat domain 35 57539 [link]
hsa DYNC2H1 dynein cytoplasmic 2 heavy chain 1 79659

Pubmed ID Priority Text
24624349 0.96 DYNC2H1, EBP, EVC, EVC2, FGFR3, IFT80, IFT122, LEPRE1, NEK1, PEX7, PPIB, SLC26A2, SLC35D1, SOX, TRIP11, and WDR35, have been identified to be involved in AO-like lethal skeletal dysplasias.
24465567 0.93 DYNC2H1, as well as another retrograde motor component, WDR34, and IFT43, WDR35 (IFT121), and WDR19 (IFT144; Figure 3B).
22829176 0.91 WDR35/IFT121, TTC21B/IFT139, WDR19/IFT144, IFT140, IFT43, and DYNC2H1, a subunit of the cytoplasmic dynein motor 2.
0.55 WDR35 and DYNC2H1 are mutated in both milder and more severe phenotypes.
26130459 0.80 WDR35 = SRTD7 and CED2; WDR34 = SRTD11; WDR60 = SRTD8; DYNC2H1 = SRTD3; DYNC2LI1 = novel intermediate phenotype of our patients).
27453244 0.80 DYNC2H1/TTC21B/WDR19/NEK1/WDR35/WDR60/IFT140/IFT172/WDR34/CEP120/KIAA0586.
27925158 0.80 DYNC2H1 (OMIM 603297) and DYNC2LI1 (OMIM 617083)], the IFT-A retrograde transport complex [WDR19 (OMIM 608151), WDR34 (OMIM 613363), WDR35 (OMIM 613602), WDR60 (OMIM 615462)], IFT140 (OMIM 614620), TTC21B (OMIM 612014) and TCTEX1D2], the IFT-B anterograde transport complex [IFT80 (OMIM 611177) and IFT172 (OMIM 607386)], basal body and centrosomal proteins [EVC1 (OMIM 604831), EVC2 (OMIM 607261), KIAA0586 (OMIM 610178) and CEP120 (OMIM 613446)], a planar cell polarity component [INTU (OMIM 610621)], as well as kinases and related ciliary molecules [ICK (OMIM 612325), NEK1 (OMIM 604588)], C21ORF2 (OMIM 603191), among the skeletal ciliopathies.



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