Publication for PSMB8 and PSME1
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | PSMB8 | proteasome 20S subunit beta 8 | 5696 | [link] | ||
| hsa | PSME1 | proteasome activator subunit 1 | 5720 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 28543773 | 0.98 | PA28alpha, LMP2, LMP7) while progressively decreasing expression of constitutive catalytic proteasome subunits (beta1, beta2, beta5) and that the loss of constitutive proteasome subunits continues (15 days) beyond the time at which immunoproteasome induction is maximal (9 days). |
| 0.97 | PA28alpha, (C) LMP7 and beta5, (D) beta2 and (E) LMP2 and beta1 protein expression relative to vehicle after normalization. | |
| 0.96 | PA28alpha, LMP7, and LMP2 were significantly increased starting at 10 pg/mL IFNgamma, with significantly enhanced induction observed at 1 ng/mL IFNgamma (Fig 6B,C and Supp. | |
| 0.93 | PA28alpha and LMP7) and that this increased expression associates with neurocognitive impairment, particularly with neuropsychological subtests associated with executive functioning and speed of processing. | |
| 0.88 | LMP7 (Fig. 2A) and PA28alpha (Fig. 2D) protein in both HIV-positive and HIV-negative individuals. | |
| 0.85 | PA28alpha, (C) LMP7, and beta5 protein expression relative to vehicle after normalization to beta-tubulin. | |
| 0.82 | LMP7 (A, B, C) and PA28alpha (D, E, F) was determined by Western blot in DLPFC samples. | |
| 21256843 | 0.98 | PA28A, LMP7, and MECL-1 occurred in the non-neoplastic part of a liver removed for hepatocellular carcinoma (Fig 3). |
| 0.97 | LMP7, MECL-1 and PA28alpha/beta has been shown to increase in proportion to the degree of chronic inflammation, in both controls and chronic liver disease. | |
| 25127410 | 0.98 | Psmb8/beta5i as well as of the PA28alpha/PA28beta subunits are detected upon embryoid body-mediated differentiation. |
| 19443843 | 0.97 | PSME1 (siE1, 50 nM), PSMB8 (siB8, 50 nM), or a mixture of both (siMIX, 25 nM each). |
| 0.97 | PSME1, PSME2, and PSMB8 were quantitated by qRT-PCR. | |
| 0.96 | PSMB8/LMP7 and PSME1 (25 nM each) was equally effective at reversing the IFNgamma effect. | |
| 31114588 | 0.97 | PSMB8 (beta-5i) and PA28alpha compared with control cells. |
| 0.74 | PSMB8, PA28a, PSMD2, PSMA4, PSMA2, and PI31. | |
| 31505885 | 0.97 | PSMB8, PSMB10, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6, PSMD3, PSMD4, PSMD11, PSME1, PSMF1, and PSMD6) in CRC was evaluated using the PROGgeneV2 database . |
| 0.95 | PSMB8, PSMB10, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6, PSMD3, PSMD4, PSMD11, PSME1, PSMF1, and PSMD6) of the proteasome system (Table S2) were used as a combined gene signature for the miR-21-mediated downregulation of the proteasome pathway. | |
| 20174631 | 0.97 | LMP7) and PA28-alpha subunits. |
| 28218682 | 0.97 | LMP7, LMP10, PA28-alpha, and PA38-beta, while TAP1 and TAP2 are expressed in low abundance. |
| 22349260 | 0.96 | PA28-alpha/beta or for the three inducible proteasomal subunits LMP2/MECL1/LMP7 (IP), respectively. |
| 0.96 | PA28-alpha, PA28-beta, LMP2, MECL1 and LMP7, as indicated. | |
| 28719601 | 0.96 | Psmb8, Psmb9, Psmb10, Psme1 and Psme2) that are known to function together in a specialized "immunoproteasome" involved in antigen presentation by the immune cells. |
| 27589570 | 0.95 | PSMB8, PSMB9, PSMB10, PSME1, TAP1, TAP2, TAPBP) were present in the PDL1 breast and GIST signatures, but not in the pancreatic signature, notably on the aspects of TAP-dependent mechanisms of antigen presentation, endocytosis, phagosome maturation (CYBB, LTF, NCF1, NCF2, NCF4, RAB31) and proteasomal ubiquitin-independent protein catabolic process. |
| 28051153 | 0.90 | PSMB8, PSMB9 and PSMB10), proteasome activators PSME1 and PSME2 and transporter genes TAP1 and TAP2 across cancer cells, and eight datasets representing breast cancer tumour tissue's. |
| 31618209 | 0.90 | PSMB8, PSME1). |
| 29463848 | 0.84 | PSMB8, PSME1, IRF1, SAMD9L, DTX3L, IFI35, and NMI, exhibited no significant autoantigenicity (i.e. less than 1% sensitivity) in the SS subjects compared to the healthy volunteers (data not shown). |
| 9334373 | 0.78 | LMP7, and the proteasome regulator PA28alpha. |
| 24866026 | 0.72 | PA28alpha and PA28beta regulator subunits and of the inducible catalytic subunits LMP2, LMP7 and MECL1, with respect to immature IL-4-DCs. |
| 31015447 | 0.71 | PSMB8, PSMB9, BST2, IRF1, IRF9, CD74, PSME1, PSME2, HLA-DQA1/DPA1/ DPB1/DRA/ DQB2/DRB1/ DQB1/DMA/DMB/DOA, HLA-A/B/C/E/F) and include the inhibitory receptor LAG3. |
| 24023820 | 0.70 | PSME1, PSMB10, PSMB9 and PSMB8) (table 2). |
| 26437235 | 0.68 | PSMB8 (proteasome subunit beta type-8), PSMB9, and PSMB10 that are integral parts of the immune-proteosome, or genes whose proteins contribute to its regulation: PSME1 and PSME2. |
| 28174229 | 0.56 | PSME1, PSME2, PSMB8, PSMB9, SAMDH1, SOD2, STAT1, STAT2, and WARS. |
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