Publication for Cldn7 and Prss8

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Cldn7	claudin 7	53624			[link]
mmu	Prss8	protease, serine 8 (prostasin)	76560

Pubmed ID	Priority	Text
30623107	0.98	Prss8-matriptase axis in the intestinal epithelial cells and dysregulation of this axis results in excess Epcam cleavage by matriptase and destabilization of the Epcam/claudin-7 complex.
	0.97	Prss8 suppressed Epcam cleavage, stabilized claudin-7 levels (Fig. 8c, d) and rescued destruction of crypt organoids caused by Hai-2 ablation (Fig. 8e).
	0.97	Prss8 and Spint2 in organoids relieved the Epcam cleavage in the absence of Hai-2, and consequently maintained the claudin-7 levels and rescued organoids from subsequent rupture.
	0.92	claudin-7 loss were alleviated by Prss8 ablation.