Publication for St14 and Cldn7

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu St14 suppression of tumorigenicity 14 (colon carcinoma) 19143 [link]
mmu Cldn7 claudin 7 53624

Pubmed ID Priority Text
29617460 0.99 matriptase has been shown to cleave EpCAM in cultured intestinal epithelial cells, causing premature degradation of the tight junction protein claudin-7.
0.98 claudin-7 expression in Spint2-/-;Prss8R44Q/R44Q mice mimic closely molecular changes induced by unregulated matriptase activity in HAI-2-silenced intestinal cell monolayers.
30623107 0.98 matriptase axis in the intestinal epithelial cells and dysregulation of this axis results in excess Epcam cleavage by matriptase and destabilization of the Epcam/claudin-7 complex.
0.96 matriptase-selective synthetic inhibitor ZFH7185-8 suppressed the Hai-2 loss-induced Epcam cleavage in a dose-dependent manner, accompanying stabilization of claudin-7 (Fig. 9c).



The preparation time of this page was 0.0 [sec].