Publication for Cdh1 and Cldn7

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Cdh1	cadherin 1	12550			[link]
mmu	Cldn7	claudin 7	53624

Pubmed ID	Priority	Text
23284647	0.98	E-cadherin, Tjp2, Cldn4 and Cldn7), Wnt ligands (Wnt7A, Wnt7B), and possibly microRNA (miR-200s).
	0.95	Cdh1, Cldn4, Cldn7, Dsg2, Gjb3, Tjp2, Esrp1, Rab25, and Epcam (Figure 4J).
	0.83	Cdh1), tight junction (Cldn7, Cldn4, Cldn3, Ocln and Tjp2), desmosomes (Dsp, Jup, Pkp2 and Dsg2), gap junction (Gjb3), cytokeratine (Krt7, Krt8, Krt14, Krt17 and Krt19), Integrin (Itgb6, Itgb4 and Itgb2), Wnt ligands (Wnt7A, Wnt7B) and epithelial specific splicing factor (Esrp1).
28439535	0.98	Cdh1, Cldn7, mir200a, Snai1, Twist1, Tgfb1, and Zeb1 that are related to EMT was a key feature of the FGM sarcoma subgroup (Table 1 and table S1).
	0.96	CDH1+ MDSTs to four distinct proteomic clusters (Fig. 4B, clusters 2 to 5), two MMTV-cMYC transgenic MDSTs to a closely related but distinct cluster (Fig. 4B, cluster 6), and all five FGM MDSTs to a single cluster (cluster 1) primarily driven by a proteomic signature characterized by low expression levels of beta-catenin, claudin-7, and E-cadherin proteins (Fig. 4B, signature 1), consistent with the biology of these cancers being linked to EMT-related processes (table S1).
	0.72	claudin-7, HER3, beta-catenin, and E-cadherin proteins.
30015855	0.98	claudin-7 complex, together with E-cadherin, is essential to keep the balance between AJs and cortical tension.
	0.96	claudin-7, together with E-cadherin, are essential to keep the balance between AJs and cortical tension (Fig. 2A).
	0.87	E-Cadherin, EpCAM, claudin-7, other claudins, occludin and other junction connections is equal with the cortical tension between two epithelial cells; but the direction of the total pulling force is opposite to that of cortical tension.
19056388	0.98	E-cadherin and claudin-7.
	0.89	claudin-7, and E-cadherin staining; Figure 4A,B, data not shown).
18593559	0.98	claudin 7 (Cldn7), occludin (Ocln), and E-cadherin (Cdh1) within 24 hr of induction (day 3), with further inhibition on day 4 (Figure 2B).
22162632	0.98	E-cadherin, claudin-3, claudin-4, and claudin-7 and represses the expression of those genes, thereby inducing EMT.
24603431	0.98	claudin7 revealed similar localization in wild type and dko UBs (Figure S6L-M) suggesting that MAPK activity is specifically involved in regulating E-cadherin mediated AJs.
24665377	0.98	E-cadherin and Claudin 7 signals and an increase in mesenchymal markers such as Vimentin and Lipocalin 2 23.
29371425	0.98	E-Cadherin/Cdh1, Epcam, Cldn6 and Cldn7 were upregulated in single Mesp1 KO cells (Fig. 2D-F and Table S1), consistent with the defect of exiting the pluripotent epiblast stage.
31121840	0.98	E-cadherin and claudin-7 from membrane to intracellular foci.
29617460	0.97	claudin-7, claudin-1 and E-cadherin, but an increase in gene and protein expression of claudin-4.
	0.96	E-cadherin and claudin-7, and an increased expression of claudin-4 on postnatal days 2 and 4.
	0.93	E-cadherin (50% on P2, 55% on P4), claudin-7 (60% on P2, 44% on P4) and occludin (unchanged on P2, 54% on P4) (Fig 5C and 5D).
	0.90	E-cadherin, and claudin-7, indicating that the phenotype of Spint2-/-; Prss8R44Q/R44Q mice recapitulates early events in the development of CTE in humans and provides an excellent model for study of the etiology and treatment of this debilitating disease.
31835702	0.97	CLDN7, TJP1, TJP2, F11R, and CDH1 in YAP knockdown embryos (p < 0.05; Figure 5A, middle panel).
	0.97	CLDN7, TJP1, TJP2, and F11R), adherens junction formation (CDH1), and fluid accumulation (AQP3 and ATP1B1).
19153598	0.97	E-cadherin, occludin and claudin-7 expression, increases vimentin and N-cadherin expression, and enhances migration and invasion.
22848790	0.97	Cdh1 and Cldn-7 was induced by about 227 and 31-fold, respectively in ES cells (Figure 4b-c, Red bars).
28783170	0.97	claudin-7, Occludin, ZO-1, E-cadherin, beta-catenin and beta1-integrin (p<0.01; Fig-1A and Supplementary Fig-S1A).
23766441	0.96	claudin-7 expression while expression of claudin-3,-4,15, Occludin, E-cadherin, and beta-catenin remained largely unaltered (Figure 1E,1F and S2-B).
21924257	0.95	Cldn7), adherens junctions (Cdh1, Cdh16) and desmosomes (Eppk1, Dsg2) are found among the 113 genes present in TLCEG (Table 3).
24123696	0.94	Claudin-7 and E-cadherin when compared to Dclk1flox/flox (Fig. 3C).
	0.79	Claudin-7, as well as E-cadherin in Villin-Cre;Dclk1flox/flox mice (Fig. 4B).
	0.72	Claudin-7, E-cadherin in Villin-Cre;Dclk1flox/flox (lane 2) mice compared to Dclk1flox/flox.(lane 1) (C) Immunohistochemistry for E-cadherin demonstrates strong membranous staining in the Dclk1flox/flox mice but diffuse cytosolic staining in Villin-Cre;Dclk1flox/flox mice indicative of protein degradation (200X - insets ~600X).
24590763	0.94	E-cadherin we observed in SPs are functionally related to the changes in Claudin-2 expression, as shown for Claudin-7, or brought about by changes in inflammation-associated cytokine expression.
29391007	0.93	ECAD and CLDN7 were largely basolateral, with some apical staining present in certain cell types.
	0.83	CLDN7, whose mRNA levels were strongly modulated by cell type, and also the expression of ZO-1, whose deletion disrupts TJs, OCLN, which regulates macromolecular TJ permeability, and ECAD, a structural protein associated mainly with adherens junctions.
	0.75	E-cadherin and claudin-7 marked mainly the basolateral membrane, while claudin-2, ZO-1, and occludin resided in the apical membrane.
22044670	0.92	Cldn7-/- intestines, while E-cadherin expression was only decreased in P5 Cldn7-/- intestines (Fig. 7A).
	0.71	E-cadherin, was decreased in P0 Cldn7-/- intestines (left), while both integrin alpha2 and E-cadherin signals were reduced in P5 Cldn7-/- intestines (right).
26285154	0.91	Claudin-7 and E-cadherin, and moderate decreases in Claudin-1, -5 (Fig 2C).
27628423	0.88	ECAD/CLDN7) cells to mesenchymal (FSP1/ZEB1) staining within each size group revealed that single cells and nano-metastases exhibited comparable frequencies of cells positive for these epithelial and mesenchymal markers; by contrast, larger lesions had a significantly greater fraction of epithelial cells (Supplementary Fig. 3).
21460854	0.80	cadherin-1, Epcam, claudin4, and claudin7, that are highly expressed in 4T1-miR-155 cells and represent genes that are over-expressed in 4T1-miR-155 epithelial cells.
22535153	0.67	E-cadherin, ZO-1 and claudin 7 (data not shown).