Publication for RECQL4 and RTEL1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	RECQL4	RecQ like helicase 4	9401			[link]
hsa	RTEL1	regulator of telomere elongation helicase 1	51750

Pubmed ID	Priority	Text
31597307	0.98	RTEL1 and RECQL4.
	0.98	RTEL1, RECQL4, BLM, DNA2, FEN1, Timeless, or TOP2A) results in replication stress characterized by multiple telomeric signals and sister-telomere associations during metaphase, a phenotype defined as fragile telomere.
	0.94	RTEL1, and RECQL4), either helping in G4 unwinding or in D-loop unlocking, are depicted.
23300679	0.97	RECQL4 region had the strongest association with the risk of melanoma (gene-based P-value = 2.5x10-3; Table 2, Table S2 and Figure S2) and the RTEL1 region had the strongest association with risk of dysplastic nevi (gene-based P-value = 0.004; Table 3, Table S3 and Figure S4).
	0.97	RECQL4, RTEL1 and TERF2 were associated with melanoma, the presence of dysplastic nevi and number of nevi, respectively, in the Italian combined study.
	0.95	RECQL4, a gene involved in genome stability, RTEL1, a gene regulating telomere elongation, and TERF2, a gene implicated in the protection of telomeres, were associated with melanoma, the presence of dysplastic nevi and number of nevi, respectively.
27342280	0.97	RECQ4, RTEL1 and PIF1, have been implicated in the unwinding of G-quadruplexes as well, and mutations in these helicases are similarly associated with genome instability and genetic disorders.
	0.94	RTEL1; the RecQ-family helicases BLM, WRN and RECQ4; and PIF1.
29895583	0.97	RECQL4), Shelterin (ACD, TINF2), and Telomerase (DKC1, WRAP53) pathways; 10 DNA repair genes linked to telomeres (BTBD12, DCLRE1C, DDB1, FEN1, HMBOX1, MSH2, PARP3, RAD51L3, RAD54L, and SIRT6); and seven other TRGs (BICD1, CLPTM1L, MAD1L1, MTRR, MYC, RTEL1, and SIP1).
	0.93	RECQL4), Shelterin (ACD), and Telomerase (DKC1) pathways; eight CpGs on six TRGs in the DNA repair pathway (DCLRE1C, DDB1, MSH2, PARP3, RAD51L3, and SIRT6); and one CpG on each of BICD1, CLPTM1L, MAD1L1, MTRR, RTEL1, and SIP1.
27308340	0.97	RECQ4, RECQ5, RTEL1, and WRN (Table 1) (Rogers, van Kessel, and Bochman, in press).
28981702	0.97	RecQL4, RecQL1, RTEL1 have been tightly implicated in telomere maintenance mediated by TRF2.
29255170	0.97	RECQ4, RECQ5, RTEL1) and analysed RPA-positive UFB formation.
29273621	0.97	RECQL4, and RECQL5) and Fe-S (FANCJ, RTEL1, XPD, and DDX11) families to act on unique structures in nucleic acid metabolism.
31287417	0.97	RECQL4, RTEL1 and DHX36, alongside many others with no known G4 link (see Figure 10A).
25990736	0.80	RecQL4, RecQL1 and RTEL1 have been implicated in telomere maintenance.
20637196	0.54	RecQ4 Mm, BAD11131; RecQ5 ce, CAA86232; RecQ5 Dm, AAD43051; RecQ5 Gg, BAI79325; RecQ5 Hs, NP_004250; RecQ5 Mm, BAD11130; Rqh Sp, CAA91177.1; RTEL1 Hs, NP_116575; RTEL1 Ce, NP_492769; RTEL1 Mm, AAI44979; Sgs1 Sc, AAB60289.1; WRN Gg, BAI79323; WRN Hs, AAC63361; WRN Mm, AAH60700; WRN Xl, NP_001081838; WRN1 Ce, NP_495324.