Publication for NFKBIA and TNIP1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	NFKBIA	NFKB inhibitor alpha	4792			[link]
hsa	TNIP1	TNFAIP3 interacting protein 1	10318

Pubmed ID	Priority	Text
22158561	0.98	NFKBIA (NF-kappaB inhibitor alpha), TNFAIP3 (tumor necrosis factor alpha induced protein 3) and TNIP1 (TNFAIP3 interacting protein 1) genes.
24598827	0.98	ABIN1, ABIN2, IkappaBalpha, IkappaBbeta, and actin proteins as indicated in Methods.
30846988	0.98	IkappaBalpha, TNFAIP3 interacting protein 1 (TNIP1), and OAS1.
30761389	0.97	NFKBIA (encoding IkappaBalpha) and TNIP1 (encoding ABIN-1).
	0.93	ABIN-1 inhibits IL-17-dependent NF-kappaB signaling upstream of IkappaBalpha degradation.
	0.92	ABIN-1 is required to inhibit IL-17-dependent NF-kappaB signaling upstream of IkappaBalpha.
	0.91	ABIN-1-/- cells transfected with a control (empty) vector (E.V.), IkappaBalpha was degraded within 15 minutes following IL-17 stimulation and remained at low levels for as long as 60 minutes post-stimulation (Fig. 3A, lanes 5-8).
	0.82	ABIN-1-/- fibroblasts reconstituted with ABIN-1, IkappaBalpha was restored to basal levels by 60 minutes (Fig. 3A, lane 4).
	0.61	IkappaBalpha, A20 and Regnase-1/MCPIP1, all of which are regulated by NF-kappaB. ABIN-1 is also a known NF-kappaB target gene, raising the possibility that IL-17 might also induce its expression.
26573299	0.97	IkappaBalpha is encoded by NFKBIA), which normally form cytoplasmic complexes with NF-kappaB. Once phosphorylated, IkappaB is subject to ubiquitin-induced proteasomal degradation, resulting in the nuclear translocation of NF-kappaB. Further, the protein products of TNFAIP3 and TNIP1, A20 and ABIN1, respectively, physically interact to enable the ubiquitin-mediated destruction of NEMO (a regulatory protein that activates IKK).
	0.79	TNIP1, NFKBIA, REL and TRAP3IP2 (Fig. 3).
23793113	0.97	IkappaBalpha, A20, CYLD, and ABIN1.
25033461	0.95	IkappaBalpha, IkappaBbeta, ABIN-1 and ABIN-2 are known negative regulators of NF-kappaB, and in light of our previous studies demonstrating diminished expression of these negative regulators of NF-kappaB signaling in MPM and MB cells that were exposed to CFM-4, here we tested whether treatments of NB cells with CFM-4 or CFM-5 also reduced expression of IkappaBalpha, IkappaBbeta, ABIN1 and ABIN2 proteins.
	0.93	ABIN1, ABIN2, IkappaBalpha, IkappaBbeta, alpha-tubulin and actin proteins as indicated in Methods.
25854761	0.95	TNIP1, NFKBIA, IL12B and LCE3D-LCE3E.
	0.95	TNIP1, NFKBIA, IL12B and LCE3D-LCE3E.
31365872	0.93	IkappaBalpha, A20, and ABIN1.
28166199	0.92	TNIP1, TNIP2, NFKBIA, TNFAIP3) with other gene transcripts in 413 glioblastomas (significance level: P<1 x 10-5).
	0.91	NFKBIA, TNFAIP3, TNIP1 and TNIP2 representing pairwise associations between each of these variables in 188 glioblastomas.
	0.88	TNIP1, TNIP2, NFKBIA and TNFAIP3 genes.
	0.71	TNIP1, TNIP2, NFKBIA and TNFAIP3 in LN229 (d), BTSC23 (e), BTSC233 (f) cells expressing EV, KLF6-wt or KLF6-sv1.
	0.54	NFKBIA, TNFAIP3, TNIP1 and TNIP2).
26215033	0.92	TNIP1, TNFAIP3, NFKBIA, ZC3H12C, IL36RN, SOCS1).
26780035	0.92	NFKBIA, PSMA6, ERAP1, TRAF3IP2, IL12RB2, IL23R, IL12B, TNIP1, TNFAIP3, TYK2) and geoepidemiologic factors that contribute to the wide variability seen in psoriasis.
24175098	0.91	TNIP1, TNFAIP3, IL23A, IL13, TRAF3IP2, LCE3B/3C, RNF114, IFIH1, ERAP1, REL, TYK2, NFKBIA, NOS2, IL28RA, SDC4, FBXL19, and RPS26.
28537254	0.91	TNIP1, TNFAIP3 and NFKBIA) mapping to known psoriasis loci that are well-appreciated as components of NF-kappaB signalling, our results further implicate this pathway in the pathophysiology of psoriasis.
27566587	0.84	TNIP1, MAP3K7, BCL10, and NFKBIA (Figure 4).
	0.83	TNIP1 in OAML, but also identified recurrent mutations in several additional components of the NF-kappaB pathway, including BCL10 and NFKBIA.
29862142	0.83	ABIN-1 resulted in an increase and overexpression of ABIN-1 in a clear reduction of IkappaBalpha phosphorylation.
25346592	0.81	TNIP1 and NFKBIA serve as regulators of the NF-KB pathway (downstream of tumor necrosis factor-alpha [TNF-alpha]) and IL-12B, IL-23R, and TRAF3IP2 are involved in activation of the Th17immune pathway.
28617847	0.72	TNIP1, NFKBIA, REL, TYK2, IFIH1, IL23RA), Th2 pathway (IL4, IL13) and adaptive immunity involving CD8 T cells (ERAP1, ZAP70).
26143641	0.65	NFKBIA, MALT1 (strongly up-regulated), BBC3 (strongly down-regulated), TNIP1 (strongly down-regulated).
28662718	0.64	NFKBIA), and A20) and a subset of MLL1-independent genes whose expression was not significantly altered through MLL1 silencing (e.g., SOD2 and TNIP1), suggesting that MLL1 selectively regulates NF-kappaB target genes.
23448136	0.61	IkappaB-alpha, A20, tumor necrosis factor alpha-induced protein 3 interacting protein 1 (TNIP1)) of NF-kappaB signaling, hence providing context specific feedback regulation.