Publication for NDUFS2 and SDHA

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	NDUFS2	NADH:ubiquinone oxidoreductase core subunit S2	4720			[link]
hsa	SDHA	succinate dehydrogenase complex flavoprotein subunit A	6389

Pubmed ID	Priority	Text
21494430	0.98	SDHA, SDHB, SDHC and SUCLA2), fatty acid metabolism (ACAA2, ACAT1, ACSL3, ACSL4, ACSL6, ADH1, ADH6, ALDH2, CPT1A, ECHS1, EHHADH, PECI and SLC25A29,), OXPHOS (ATP5D, ATP5E, ATP5I, ATP5O, ATP6V1E1, ATPAF2, COX15, COX17, COX18, COX6C, COX7A2, MIPEP, mt-ATP8, mt-ND1, NDUFA1, NDUFA10, NDUFA4, NDUFAB1, NDUFAF1, NDUFB10, NDUFB4L1, NDUFS1, NDUFS2, NDUFV1, PPA2, SDHA, SDHB, SDHC and UQCRFS1), REDOX (GPX1, GSTZ1 and PRDX1), and neurotransmitter production and transport (ABAT, AGXT, CAD, DDC, GAD1, GLS2, GLUD1, GPT, SLC25A18 and SLC25A22).
25598486	0.97	succinate dehydrogenase [ubiquinone] flavoprotein subunit (SDHA) and NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 (NDUFS2) in ETC, and trifunctional enzyme subunit alpha (HADHA) in citric acid cycle.
29416685	0.95	NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFV1, NDUFV2, and NDUFV3), four genes for complex II succinate coenzyme Q reductase (SDHA, SDHB, SDHC, and SDHD), eight genes for complex III coenzyme Q cytochrome c reductase (BCS1L, CYC1, UQCR11, UQCRC1, UQCRC2, UQCRFS1, UQCRH, and UQCRQ), 14 genes for complex IV cytochrome c oxidase (COX4I1, COX4I2, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A2, COX7A2L, COX7B, COX8A, and COX8C), and 25 genes for complex V ATP synthase (ATP12A, ATP4A, ATP4B, ATP5A1, ATP5B, ATP5C1, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5H, ATP5I, ATP5J, ATP5J2, ATP5L, ATP5O, ATP6V0A2, ATP6V0D2, ATP6V1C2, ATP6V1E2, ATP6V1G3, LHPP, OXA1L, PPA1, and PPA2) (Figure 4A).
29843785	0.82	NDUFS2 (complex I), SDHA (complex II) and ATP5B (complex V), as well as dihydrolipoamide dehydrogenase, a component of the TCA cycle.
24953961	0.77	NDUFS2, SDHA and UQCRB.
28956814	0.64	succinate dehydrogenase A (SDHA), dihydrolipoamide dehydrogenase (DLD), ATP synthase subunit beta (ATP5B), and NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 (NDUFS2), led to mitochondrial respiratory dysfunction and a shift of energy production to glycolysis.