Publication for NDUFS2 and NDUFS3

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	NDUFS2	NADH:ubiquinone oxidoreductase core subunit S2	4720			[link]
hsa	NDUFS3	NADH:ubiquinone oxidoreductase core subunit S3	4722

Pubmed ID	Priority	Text
20426862	0.98	NDUFS2, NDUFS3, NDUFS6, NDUFS7, NDUFS8, ND1, ND4, ND5, NDUFA1, NDUFA8, NDUF13, NDUFAF1, and NDUFB9), Complex II (succinate dehydrogenase) (SDHA, SDHB, SDHC, and SDHD), Complex III (cytochrome bc 1) (UQCRB, CYTB), Complex IV (cytochrome c oxidase) [COX3 (cyclooxygenase 3)], and other genes (APP, amyloid beta, presenin-1, and alpha-synuclein).
25209663	0.97	NDUFS2) and 30 kDa (NDUFS3) core subunits through a three-helix bundle (Figs. 4, 5).
25319401	0.97	CI30, CI70), green dotted lines indicating low-pitch subjects (CI18, CI20, CI21, CI25, CI63, CI71), and red solid lines indicating nonmatched-pitch subjects (CI28, CI32, CI40, CI49, CI50, CI54, CI56, CI73).
25857492	0.97	NDUFS2, NDUFS3, NDUFS4, NDUFS6, NDUFS7) have been shown to cause different clinical phenotypes.
28259101	0.97	NDUFS2, and NDUFS3 are oxidized after reoxygenation provoking a decrease in protein stability.
27226634	0.96	NDUFS2, NDUFS3, and NDUFA5 joining with a NDUFS7-NDUFS8 sub-complex.
	0.89	NDUFS2, NDUFS3, NDUFS7, NDUFS8, NDUFA3, NDUFA5, NDUFA8, and NDUFA13) plus one mitochondrial-DNA encoded subunit ND1 and three assembly factors (NDUFAF3, NDUFAF4, and C3orf1).
	0.89	NDUFS2, NDUFS3, NDUFS8, and NDUFA5 (Fig. 9), as indicated by the preferential association of the four latter subunits with tagged-NDUFS7 (Fig. 2B).
	0.84	NDUFS2, NDUFS3, NDUFS8, and NDUFA5; the larger black dotted ellipse encompasses 26 other subunits of complex I, and the smaller ellipse contains four subunits of complex III (see supplemental Table S2).
24089531	0.96	NDUFS2, contains the core catalytic subunits NDUFS3, NDUFS7, and NDUFS8 and the membrane subunit ND1.
26053550	0.96	NDUFS2, NDUFS3, NDUFS8, NDUFV1 and NDUFV2, as well as four more common SNPs of the NDUFS7 gene in a larger sample set.
26664907	0.96	NDUFS3 and NDUFS4, which would place it close to the ubiquinone-reaction chamber formed by NDUFS2 and NDUFS7, a source of ROS during ischemia.
23828044	0.95	NDUFS2, NDUFS3, NDUFS7 and NDUFS8, which encode structural subunits of complex I. In many cases, reconstruction of these mutations resulted in specific defects in complex I stability and function, correlating well with patient delivered data and providing a deeper insight into the molecular mechanism of these deleterious changes.
28713939	0.93	NDUFS3, NDUFS2 and NDUFS1 were enriched in the Parkinson's disease, Alzheimer's disease and Huntington's disease pathways.
21680271	0.91	NDUFS2, NDUFS3, NDUFA5 and NDUFS8).
27516145	0.88	NDUFS2, NDUFS3, NDUFS7, NDUFS8, NDUFV1, and NDUFV2 being core subunits of mitochondrial complex I, we further analyzed the correlation between their IHC expression levels in clinical NSCLC specimens.
	0.83	NDUFS2, NDUFS3, NDUFS7, NDUFS8, NDUFV1, and NDUFV2.
	0.65	NDUFS2, NDUFS3, NDUFS7, and NDUFS8 belong to hydrogenase module.
22857522	0.87	NDUFS2 (S2) and NADH1 (1) and possibly NDUFS3 (S3) and NDUFS7 (S7) and whose assembly involves NDUFAF3 (AF3) and possibly C8orf38 (O38).
20819849	0.86	NDUFS2, NDUFS3, NDUFS4, NDUFS7, NDUFS8, NDUFV1, NDUFV2 and NDUFAB1) were sequenced in a cohort of 34 paediatric patients with demonstrated isolated complex I deficiency in skeletal muscle.
	0.61	NDUFS2 is located in the hydrophilic arm of complex I, close to the membrane domain, and forms part of an early peripheral arm subassembly with subunits NDUFS3, NDUFS7 and NDUFS8 (b).
19672299	0.85	NDUFS2, NDUFS3, NDUFS6, NDUFS8, NDUFV1, NDUFA6, NDUFA10, NDUFAB1, NDUFB4, NDUFB9, NDUFB10, and marginally decreased for NDUFB7.
22644603	0.85	NDUFS2, one patient with a mutation in NDUFS3, 14 patients with a mutation in NDUFS4, six patients with a mutation in NDUFS6, six patients with a mutation in NDUFS7, three patients with a mutation in NDUFS8, 17 patients with a mutation in NDUFV1 and one patient with a mutation in NDUFV2 were found.
25887158	0.84	NDUFS2, NDUFS3, NDUFA9 and others which previously reported as early assembled subunits.
20818735	0.79	NDUFS3), NuoD (NDUFS2), NuoI (NDUFS8), NuoB (NDUFS7).
26115722	0.78	NDUFS2 NDUFS3 is for oxidative phosphorylation process; EEF1D led VCP and NSFL1C to regulate Golgi/Endoplasmic Reticulum functions; SLC9A3R1 and EZR are important proteins on the cell membrane and cytoskeleton.
31249651	0.78	NDUFS3, NDUFV1, and NDUFS2.
31115493	0.75	NDUFS2, NDUFS3, NDUFS7, NDUFS8, NDUFV1 and NDUFV 2) that contain the following cofac-tors: A flavin mononucleotide (FMN) molecule; 7-9 FeS clusters [including the (2Fe-2S)N1b, (4Fe-4S)N3, (4Fe-4S)N4, (4Fe-4S)N5, (4Fe-4S)N6a/b and (4Fe-4S)N2 clusters]; and the final electron accepting iron-sulfur cluster (N2 cluster), which was recently found to deliver electrons to ubiquinone binding sites.
26462158	0.68	NDUFS2, NDUFS3, NDUFS7 and NDUFS8).
29416685	0.59	NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS6, NDUFS7, NDUFS8, NDUFV1, NDUFV2, and NDUFV3), four genes for complex II succinate coenzyme Q reductase (SDHA, SDHB, SDHC, and SDHD), eight genes for complex III coenzyme Q cytochrome c reductase (BCS1L, CYC1, UQCR11, UQCRC1, UQCRC2, UQCRFS1, UQCRH, and UQCRQ), 14 genes for complex IV cytochrome c oxidase (COX4I1, COX4I2, COX5A, COX5B, COX6A1, COX6A2, COX6B1, COX6B2, COX6C, COX7A2, COX7A2L, COX7B, COX8A, and COX8C), and 25 genes for complex V ATP synthase (ATP12A, ATP4A, ATP4B, ATP5A1, ATP5B, ATP5C1, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5H, ATP5I, ATP5J, ATP5J2, ATP5L, ATP5O, ATP6V0A2, ATP6V0D2, ATP6V1C2, ATP6V1E2, ATP6V1G3, LHPP, OXA1L, PPA1, and PPA2) (Figure 4A).
29607410	0.57	CI 49-59%), white non-Hispanic (81%, 95% CI 77-85%), and had college or graduate degrees (35%, 95% CI 30-40% and 25%, 95% CI 20-29%, respectively).
25030182	0.52	NDUFS2, NDUFS3, NDUFS7 and NDUFS8 represent the 'core' subunits which are conserved across genus along with the 7 mtDNA encoded subunits.