Publication for ACACA and HMGCS1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	ACACA	acetyl-CoA carboxylase alpha	31			[link]
hsa	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1	3157

Pubmed ID	Priority	Text
18959802	0.94	Hmgcs1), HMG CoA reductase (Hmgcr), sterol receptor binding factor-2 (Srebf2) and lanosterol 14 alpha-demethylase (Cyp51a1) (involved in cholesterol metabolism), and others including fatty acid synthase (Fasn), fatty acid binding protein (Fabp), farnesyl diphosphate synthase (Fdps), acetyl-coA carboxylase (Acaca), acetyl-coA dehydrogenase (Acadm), acetyl-coA acetyl transferase (Acat2), peroxisome proliferative activated receptor, gamma (Ppargamma) and a variety of apolipoproteins that are involved in fatty acid and triglyceride metabolism.
	0.90	Hmgcs1, Srebf2, Fabp Fasn, Fdps, Acaca, Acadm, Acat2, ApoA5, C1, E and L1 as well as Cyp27a1, Ldlr, Ppargamma and Tyms (Figure 4).
31932581	0.92	ACC1, FASN, SCD1) and cholesterol synthesis (HMGCS1, HMGCR).
	0.92	ACC1, SCD1 and HMGCS1 were observed when SIK2 was knockdown or overexpressed in A2780 and SKOV3 cells.
	0.87	ACC1, FASN, SCD1, HMGCS1 and HMGCR in A2780 and SKOV3 cells with treatment as indicated.
	0.50	ACC1, FASN, SCD1, HMGCS1 and HMGCR in A2780 and SKOV3 cells with treatment as indicated.
26632252	0.88	HMGCS1, HMGCR, LDLR, ABCA1, ABCG1, ABCG5, ACACA, FASN and CYP27B1 after over-expression or depletion of hsa-miR-195 in MCF-7 cells using real time PCR analysis (Fig. 3B).
32117236	0.87	ACACA, ACLY, HMGCR, HMGCS1, CYP51A1, and LCLAT1), while cluster 2 genes showed enrichment for the terms epidermal development (GRHL3, KRT17, SPRR1A, and SPRR1B) and tumor antigen (MAGEA2, MAGEA3, MAGEA6, and MAGEA9B) (Figure 6B), suggesting possible roles for these biological processes in the promotion of the T cell-cold phenotype.
28352810	0.85	3-hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and squalene epoxidase (SE) that are related with TC synthesis, acetyl-CoA carboxylase alpha (ACC), fatty acid synthase (FAS) and stearoyl-CoA desaturase that are related with FA synthesis.
20478529	0.72	HMGCS1, ACACA and CycE1 were determined by Real-time PCR.
30344014	0.63	HMGCS1, SQLE, and IDI1), as well as fatty acid oxidation (CPT-1) and synthesis (ACC1 and FASN) in different T cell subsets.