Publication for DDX23 and SNRNP200
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | DDX23 | DEAD-box helicase 23 | 9416 | [link] | ||
| hsa | SNRNP200 | small nuclear ribonucleoprotein U5 subunit 200 | 23020 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 21080498 | 0.98 | Prp28 and Brr2. |
| 0.96 | Brr2/200K, Snu114/116K, Prp6/102K, Prp28/100K, 40K, 15K and 52K in addition to the set of the seven common Sm proteins. | |
| 0.89 | Prp28, Brr2, U4 and U6 snRNAs. | |
| 17537823 | 0.98 | Brr2p and U5-100K/Prp28p, we noted a number not previously implicated in pre-mRNA splicing and absent from the in vitro purified spliceosomes [Table 2 ('Gg' and 'Hs' to 'N', 'R' and 'Z')]. |
| 30975767 | 0.97 | Prp28 induce movement of the U4 core domain and relocation of the Brr2 helicase. |
| 0.96 | Brr2 C-terminal helicase cassette, providing an additional example of mutually exclusive interactions of the spliceosome with Prp28 or B-complex proteins. | |
| 0.89 | Prp28-dependent transfer of the 5'SS from U1 snRNP to the U6 snRNA ACAGAGA sequence, and how this is coupled to Brr2 relocation to allow spliceosome activation. | |
| 0.84 | Prp28-N forms a long alpha helix that connects the Prp8 Jab1 domain and Brr2 C-terminal helicase cassette. | |
| 28530653 | 0.97 | Prp28 binds the Prp8N and Prp8 Endonuclease (Prp8EN) domains and Sad1 and tethers the Brr2 helicase distant from its U4 snRNA substrate. |
| 30705154 | 0.97 | Prp28 and Brr2 followed by binding of the multi-subunit Prp19-associated (NTC) and Prp19-related (NTR) complexes. |
| 29995849 | 0.95 | Brr2 is repositioned and loaded onto its U4 snRNA substrate and the B complex proteins replace Prp28 at the Prp8N domain, ready for spliceosome activation. |
| 0.95 | Prp28-mediated 5'SS transfer, Brr2 is repositioned onto its U4 snRNA substrate, guided by the B complex-specific proteins (right). | |
| 0.94 | Brr2 through its interaction with the conserved Brr2 PWI domain, and the U1 snRNP and its U1-5'SS helix are positioned near the U6 ACAGAGA region and the helicase Prp28. | |
| 0.94 | Prp28 at the Prp8N domain and induce the large movement of Brr2 to its B complex location on U4 snRNA (Fig. 5). | |
| 0.92 | Prp28, Sad1, and a repositioned Brr2 helicase. | |
| 0.90 | BRR2 helicase is held near SNU114 by the SAD1 protein and PRP28 is bound to the PRP8 N-terminal domain (PRP8N). | |
| 27377154 | 0.95 | Prp28 occurs before or during B complex formation, whereas release of U4 by the helicase Brr2 occurs during the subsequent spliceosome activation step (Fig. 7). |
| 30315277 | 0.94 | Prp28 and Brr2, respectively. |
| 0.94 | Prp28 and Brr2, respectively. | |
| 28561026 | 0.92 | SNRNP200/Brr2/U5-200K and DDX23/Prp28/U5-100K following RUVBL2 knockdown. |
| 23857713 | 0.89 | Brr2, Prp28, Snu40/52K and Dib1 [Stevens et al., ]. |
| 31409787 | 0.76 | Prp28-mediated displacement of U1 (i.e. stable B complex formation), but before the first step of the activation process, namely, unwinding of the U4/U6 duplex by Brr2. |
| 24914973 | 0.68 | Prp28 and the Ski2-like helicase Brr2. |
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