Publication for Lox and Tnc

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Lox lysyl oxidase 16948 [link]
mmu Tnc tenascin C 21923

Pubmed ID Priority Text
21912590 0.98 Tnc, Tnfrs12a, Lox, Tgfbeta3, Col3A1, and Retnla ( Figs. 7 , 8 , 9 ).
0.97 Lox), and matrix (Tnc, Tnfrsf12A, and Col3A1) genes, at the exclusion of other mechanisms (e.g. differences in growth factor, cytokine or chemokine expression) that might explain differences in growth or regenerative capacity.
32198421 0.98 Tnc, Fn1, Thbs2, Lox, and Serpinb2, have been shown to promote metastatic progression.
0.97 TNC, and SPP1), and matrix-modifying enzymes (such as serpins and lox-family proteins) are highly induced in MAFs.
25421439 0.98 tenascin-c, osteopontin, periostin, versican, lysyl oxidase (LOX), and a variety of matrix metalloproteinases (MMPs).
28468977 0.98 LOX, BMP-1, POSTN, SPARC, THBS1, TIMP1 and 2, while inhibiting TNC expression by CFBs.
31936750 0.98 tenascin-c, periostin, MMP9, collagen A1, LOX and CCL2 in the lungs.
32140621 0.98 tenascin C, and the ECM cross-linking enzyme lysyl oxidase (Lox).
27223426 0.97 Tenascin C, an extracellular matrix protein of stem cell niches, and lysyl oxidase, which regulate crosslinks of collagen IV, are critical in setting up the premetastatic environment.
27256716 0.96 LOX expression in bleomycin-induced lung fibrosis was significantly attenuated in TNC-/- mice (Fig. 5d,e).
30536712 0.96 tenascin C (TNC) as well as elevated levels of enzymes involved in matrix remodeling such as matrix metalloproteinases (MMPs) and lysyl oxidase (LOX).
26288337 0.94 tenascin-C (TN), LOX, and BMP1 being led into endoplasmic reticulum (ER) and trafficking through endoplasmic reticulum and the Golgi apparatus during secretion.
31064838 0.92 Tnc were upregulated in V-SVZ of Cre-Tat-injected Otx2-lox mice [mean +- SD: 304.6 +- 114.5% of vehicle (p < 0.0001) and 201.1 +- 94% of vehicle (p = 0.0037), respectively], reinforcing the similarity between both mouse models.
29686035 0.83 tenascin C (TN-C) and periostin, and remodeling enzymes, such as LOX, LOXL1, MMPs and TIMPs;
32083813 0.78 tenascin C (Tnc), thrombospondin 2 and 4 (Thbs2, Thbs4), transforming growth factor beta 1 (Tgfb1), alpha smooth muscle actin (Acta2), ephrin type-A receptor 4 (Epha4), asporin (Aspn), and fibromodulin (Fmod), without affecting those of collagens III and VI (Col3a1, Col6a1), eyes absent homolog 1 and 2 (Eya1, Eya2), sine oculis homeobox homolog 1 and 2 (Six1, Six2), cartilage oligomeric protein (Comp), lubricin (Prg4), biglycan (Bgn), decorin (Dcn), fibronectin (Fn), lysyl oxidase (Lox), lumican (Lum), procollagen-lysine, 2-oxoglutarate-5-dioxygenase 1 (Plod1), and transglutaminase 2 (Tgm2) in Tnmd - / - compared to WT mice (Figure 2d).
26077591 0.75 LOX protein with tenascin C expression in 47 cases of PDAC (Spearman's rho correlation coefficient = 0.61; P < 0.0001).
0.52 LOX inhibition and tenascin C expression and found a complete absence of stromal staining in LOX antibody + gemcitabine-treated mice (Fig4A right panels).



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