Publication for Fbn1 and Tnc

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Fbn1 fibrillin 1 14118 [link]
mmu Tnc tenascin C 21923

Pubmed ID Priority Text
28004808 0.98 Tenascin-C, Fibrillin 1, MMP-3, and MMP-2 as assessed by RT-PCR was induced by irradiation in wild type lung tissue (Fig. 5).
0.98 Tenascin-C, Fibrillin 1, TIMP-1, MMP-3, and MMP-2 were elevated in irradiated mouse lung, regardless of antibody treatment type (Fig. 8d).
18828875 0.98 Fbn1, MMP-2, Sparc, lamininalpha5, and tenascin-C, have similarly been identified in expression signatures related to metastases in mouse mammary cancer models.
19804646 0.98 Tnc, Eln, Fbn1, Col3A1, Col5a2 and Vcan are up-regulated, as well as two members of the Adamts metalloproteinase family (Adamts2, Adamts9).
26831464 0.98 Tnc, Fn1, Adamtsl4 and Fbn1 are involved in microfibrillar assembly and in matrix structuring, and their changes suggest an impaired elastic fiber formation.
27256716 0.97 Tsk/+ mice displayed a substantial increase in hypodermal thickness, collagen gene expression and tenascin-C accumulation in the subcutaneous loose connective tissue layer of the skin (Supplementary Fig. 10).
0.97 tenascin-C deposition in the hypodermis and alphaSMA accumulation were reduced, indicating for the first time that tenascin-C plays a role in the development of hypodermal fibrosis in the Tsk/+ mouse model of scleroderma.
0.96 Tsk/+ mouse, were ameliorated in the absence of tenascin-C, and TNC-/- mice showed accelerated fibrosis resolution.
0.90 Tsk/+ mice lacking tenascin-C showed attenuated spontaneous hypodermal thickening (Supplementary Fig. 10A).
23144868 0.97 tenascin C, osteopontin, nephronectin and fibrillin-1.
24514259 0.97 TNC-KO mice, contained genes encoding ECM proteins, including elastin, collagens, fibrillin-1 and fibulins, which are essential for aortic tissue integrity.
29472541 0.97 Fibrillin 1, Tenascin C, Biglycan, SPARC, and Col3a1 was not affected (Fig. 6e).
32121305 0.97 tendon matrix-associated molecules (Tnc, Bgn, Dcn, and Fbn1) in mouse C3H10T1/2 mesenchymal stem cells.
30036393 0.89 fibrillin-1 (FBN-1), fibulin (FBLN)-1, Latent TGF-beta Binding Protein (LTBP)-1, LTBP-4, fibrinogen, thrombospondin-1, and tenascin-C. FN is not only required for the initiation of these ECM assemblies but also for the stabilization of some of them.
27364342 0.79 tenascin-C, fibrillin-1, and alpha-2-HS-glycoprotein (aka.
31935848 0.79 Fbn1, Fbn2, Sfrp1, Tnfrsf11b, Hapln1, Igf1, and Rspo2, among others), extracellular matrix organization (Dmp1, Mmp12, Mmp19, Adamts2, Tnc, and Loxl1, among others), inflammatory response (Cxcl10, C3ar1, C4b, Ccr5, Ccl8, and Il33, among others), and Wnt signaling (Fzd1, Nfatc4, Wnt16, Sfrp1, Sfrp4, Nkd2, Prickle2, Rspo2, Rspo1, and Dkk3, among others) (Figure 3B, Table S2).
23055981 0.77 fibrillin-1, fibrillin-2, fibronectin, tenascin-C, and tenascin-W mRNAs during craniofacial development of mouse embryos between E13.5 and E15.5 using in situ hybridization, and compare them to those of Tgf-beta1 and Tgf-beta3.



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