Publication for Col1a2 and Tnc

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Col1a2	collagen, type I, alpha 2	12843			[link]
mmu	Tnc	tenascin C	21923

Pubmed ID	Priority	Text
32121305	0.98	Col1a2 Col3a1, Col5a1, Col6a1, Col14a1), and tendon matrix-associated molecules (Tnc, Bgn, Dcn, and Fbn1) in mouse C3H10T1/2 mesenchymal stem cells.
	0.98	Col1a2, Col5a1, Col6a1, Col14a1, Tnc, and Dcn gene expression in response to longitudinal lesion along the tendon axis is drastically decreased in Egr1-/- Achilles tendons, showing that Egr1 is required for the injury-induced expression of tendon-related ECM genes and key tendon markers.
18828875	0.98	Col1a2, Col1a1, Fbn1, MMP-2, Sparc, lamininalpha5, and tenascin-C, have similarly been identified in expression signatures related to metastases in mouse mammary cancer models.
20056916	0.98	Col1a2 (1.7-fold), and Tenascin-C (ten-C) (4.3-fold) (Figure 4B).
21362171	0.98	Col1a2, Tnc, Capn, Gap43 and Meis1, were up regulated in the d8DE GFP+ cells.
27256716	0.98	tenascin-C mRNA expression in these skin biopsies was accompanied by significant elevation of the fibrotic genes COL1A1, COL1A2, COL1A6, PAI-1 and COMP (P<0.01 compared to healthy controls, Mann-Whitney U).
27527664	0.98	Col1a2, Col14a1, Tnc and Dcn (Fig. 5a,b).
24586654	0.97	Tnc is highly interconnected with other fibrosis-associated genes (R.H. and F.L., unpublished observations); in particular, it is significantly correlated with the hepatic expression levels of collagens (Col1a2: r = 0.76; p = 0.002; Col3a1: r = 0.75; p = 0.001) and Tgfb1 (r = 0.74; p = 0.002).
	0.96	Tnc highly correlates with other fibrosis-associated genes, in particular with hepatic expression levels of collagens (Col1a2: r = 0.76; p = 0.002; Col3a1: r = 0.75; p = 0.001) and transforming growth factor beta 1 (Tgfb1: r = 0.74; p = 0.002).
27760209	0.97	Col1a2, Tnc, Acta2, Fbn2, Timp1, Kim1 were specifically upregulated in the pristane-SNF1 model (S1 File).
	0.95	Tnc, Kim1, Col1a2, Acta2, Timp1 had a greater increase in kidneys of pristane-SNF1 model compared to the ADV-IFNalpha BWF1 model (Fig 6A).
30536712	0.97	tenascin C (TNC), cadherin related family member 1 (PCDH21), matrix metalloproteinase 14 (MMP14), collagen type I alpha2 chain (COL1A2), matrix metalloproteinase 12 (MMP12), fibulin 2 (FBLN2), elastin (ELN), fibrinogen alpha chain (FGA); correlation coefficient = 0.950, 0.949, 0.881, 0.834, 0.830, 0.824, 0.823, 0.738, respectively (Fig. 4 c).
31434209	0.97	Col1a2, Adam12, Ctgf, TNC, Wisp1, Elastin, and Fibrillin as highly expressed genes, amongst others.
32015383	0.97	col1a2, periostin, tenascin C, fibronectin 1, beta1-integrin, CAP, ALP, Runx-2 and OCN.
25760325	0.96	COL1A2 and tenascin C promoters, there was surprisingly no difference in fibrosis after either UUO or aristolochic acid-induced injury although renal MPIC lacking TbetaRII had a significant reduction in collagen I production in vitro and transcription in vivo.
	0.95	COL1A2-Cre and TNC-Cre implies that these cells may perform similar functions after injury.
28339476	0.96	Col1a2 logFC = 1.46) or fibronectin (Fn1, logFC = 1.77) were highly up-regulated in addition to genes encoding matricellular proteins like osteopontin (also known as secreted phosphoprotein-1, Spp1, logFC = 5.81), tenascin-C (Tnc, logFC = 2.81) or thrombospondin-1-4 (Thbs1, logFC = 1.76; Thbs2, logFC = 0.73; Thbs3, logFC = 0.67 Thbs4, logFC = 2.07).
27129287	0.92	Col1a2, Fn1, Col5a2, Col3a1, Thbs4, Spp1, Tnc, Thbs2 and Comp) were annotated in the pathway of ECM-receptor interaction, which were mostly significantly enriched with the differentially expressed genes in the MI samples compared with the sham control ones (P=5.66E-16).
	0.83	Col1a2, Fn1, Tnc and Tlr4) and was significantly enriched with differentially expressed genes (P=8.78E-10).
	0.83	Tnc, Col5a1, Comp, Col5a2, Fn1, Thbs4, Col1a2 and Thbs2), the protein digestion and absorption signalling pathway (annotated with Col1a1, Col14a1, Col5a1, Col1a2, Col12a1, Col3a1, Col5a2, Kcnq1 and Cpa3) and the Toll-like receptor signalling pathway (annotated with Tlr4, Ctsk, Tlr8 and Spp1) were all significantly enriched with the differentially expressed genes in the MI samples compared with the sham control samples (Table 1).
27773427	0.91	COL1A2 or Tenascin-Cre.
29257130	0.68	Tnc and Col1a2), or growth factor-binding proteins (Igfbp3 and Igfbp5).