Publication for Col8a1 and Tnc
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Col8a1 | collagen, type VIII, alpha 1 | 12837 | [link] | ||
| mmu | Tnc | tenascin C | 21923 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 24069556 | 0.98 | COL8A1, OPN, BGN, TNC, PAI-1, CTGF, TSP1, TIMP1, MMP-12, MCP-1, IL2RB, IL15, MCP3, and BCL2A1). |
| 32130914 | 0.97 | Tnc were significantly higher in the scar during the proliferation phase (d5), while MFC markers Ecrg4, Comp, Sfrp2, Thbs4, Wisp2, Meox1, and Col8a1 were upregulated at d14. |
| 32248062 | 0.97 | Col8a1, Col12a1, Col16a1, Col11a1, Tnc, Fbn2, and Adam12. |
| 28339476 | 0.96 | Col8a1, logFC = 2.37; Col12a1 logFC = 1.83; Col1a2 logFC = 1.46) or fibronectin (Fn1, logFC = 1.77) were highly up-regulated in addition to genes encoding matricellular proteins like osteopontin (also known as secreted phosphoprotein-1, Spp1, logFC = 5.81), tenascin-C (Tnc, logFC = 2.81) or thrombospondin-1-4 (Thbs1, logFC = 1.76; Thbs2, logFC = 0.73; Thbs3, logFC = 0.67 Thbs4, logFC = 2.07). |
| 21911454 | 0.95 | Tenascin C (4.5 fold, p=0.006), Fibronectin 1 (5.88 fold, p=0.01), Collagen type I, alpha 1 (30.3 fold, p=0.03), Collagen type VIII, alpha 1 (2.63 fold, p= 0.018), Collagen XV, alpha 1 (3.22 fold, p= .045), and Cysteine rich protein 61 (15.2 fold increase, p= 0.02), Thus, our array data suggest a tumor microenvironment characterized by enhanced TGF-beta activity in the stromal compartment. |
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