Publication for EWSR1 and HNRNPK

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa EWSR1 EWS RNA binding protein 1 2130 [link]
hsa HNRNPK heterogeneous nuclear ribonucleoprotein K 3190

Pubmed ID Priority Text
26573619 0.96 EWS influence HNRNPK splice site selection.
0.94 EWS depletion caused a significant increase of HNRNPK transcripts, which used the distal exon 16 splice acceptor site (D) (Fig 6a-c and Additional file 13).
0.92 EWS, and Ac-H3K9 enrichment peaks are shown for the ACPT and C19orf48 gene complex (with p values scored number 7 of the 103 peaks and 16 of the 41 peaks for EWS and FUS, respectively), RCC1 and SNHG3 gene complex (with p values scored number 5 of the 103 peaks and 3 of the 41 peaks for EWS and FUS, respectively), and HNRNPK gene (with p values scored number 34 of the 103 peaks and 26 of the 41 peaks for EWS and FUS, respectively) (Fig. 2a-c).
0.87 HNRNPK gene, we observed a FUS and EWS function on alternative splice site selection at the last exon.
18698806 0.96 hnRNPK; (C) phosphopeptide QDHPSSMGVpYGQESGGFSGPGENR derived from Ewing sarcoma breakpoint region 1; (D) phosphopeptide IGGDAGTSLNSNDpYGYGGQK derived from FUSE-binding protein 1; (E) phosphopeptide GPSpYGLSAEVK derived from Calponin-3; (F) phosphopeptide TGAPQpYGSYGTAPVNLNIK derived from FIP1-like 1.
26885691 0.95 EWS-FLI1/RHA or EWS-FLI1/p68 complexes are impaired by YK-4-279 treatments, EWS-FLI1 mediated alternative splicing events are affected, although binding of EWS-FLI1 to the splicing regulators PRPF6 and hnRNP K is not influenced.
27816050 0.95 HNRNPK, and functioned as an oncogene through regulating gene expression downstream of EWS-FLI1 in Ewing sarcoma.
30087896 0.95 EWS, HNRNPK, ZC3H6, UBAP2L, and TARDBP (Table 2).



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