Publication for EWSR1 and HNRNPK
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | EWSR1 | EWS RNA binding protein 1 | 2130 | [link] | ||
| hsa | HNRNPK | heterogeneous nuclear ribonucleoprotein K | 3190 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 26573619 | 0.96 | EWS influence HNRNPK splice site selection. |
| 0.94 | EWS depletion caused a significant increase of HNRNPK transcripts, which used the distal exon 16 splice acceptor site (D) (Fig 6a-c and Additional file 13). | |
| 0.92 | EWS, and Ac-H3K9 enrichment peaks are shown for the ACPT and C19orf48 gene complex (with p values scored number 7 of the 103 peaks and 16 of the 41 peaks for EWS and FUS, respectively), RCC1 and SNHG3 gene complex (with p values scored number 5 of the 103 peaks and 3 of the 41 peaks for EWS and FUS, respectively), and HNRNPK gene (with p values scored number 34 of the 103 peaks and 26 of the 41 peaks for EWS and FUS, respectively) (Fig. 2a-c). | |
| 0.87 | HNRNPK gene, we observed a FUS and EWS function on alternative splice site selection at the last exon. | |
| 18698806 | 0.96 | hnRNPK; (C) phosphopeptide QDHPSSMGVpYGQESGGFSGPGENR derived from Ewing sarcoma breakpoint region 1; (D) phosphopeptide IGGDAGTSLNSNDpYGYGGQK derived from FUSE-binding protein 1; (E) phosphopeptide GPSpYGLSAEVK derived from Calponin-3; (F) phosphopeptide TGAPQpYGSYGTAPVNLNIK derived from FIP1-like 1. |
| 26885691 | 0.95 | EWS-FLI1/RHA or EWS-FLI1/p68 complexes are impaired by YK-4-279 treatments, EWS-FLI1 mediated alternative splicing events are affected, although binding of EWS-FLI1 to the splicing regulators PRPF6 and hnRNP K is not influenced. |
| 27816050 | 0.95 | HNRNPK, and functioned as an oncogene through regulating gene expression downstream of EWS-FLI1 in Ewing sarcoma. |
| 30087896 | 0.95 | EWS, HNRNPK, ZC3H6, UBAP2L, and TARDBP (Table 2). |
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