Publication for Scd2 and Fads2

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Scd2	stearoyl-Coenzyme A desaturase 2	20250			[link]
mmu	Fads2	fatty acid desaturase 2	56473

Pubmed ID	Priority	Text
24074869	0.98	Fads2, Scd1 and Scd2.
	0.97	Fads2, Elovl5 and Scd2 (Fig. 5A).
	0.81	Fads2, involved in the elongation and desaturation of long chain fatty acids to generate anti-inflammatory PUFAs, and Scd1/Scd2 which catalyze the synthesis of 16:1 POA, suggested to be an insulin sensitizing adipokine.
	0.75	Fads2, Elovl5, and Scd2 (Fig. S3A-C).
	0.64	Fads2, Elovl5, and Scd2 in both WT and MNKO macrophages.
25147951	0.98	Fads2, Scd2, Stard4, Ldlr, Insig-1, and Fdps, which are direct targets of SREBPs and involved in the cholesterol/lipid biosynthetic pathways, are down-regulated in S1Pcko cartilage (Table 2) mirroring that seen in the microarray.
	0.97	Scd2, Ldlr, Fads2, and Fdps genes at the RNA level in the humerus of S1Pcko mice (Fig. 8).
	0.91	Scd2, Ldlr, Fads2, and Fdps genes at the RNA level, shown by in situ hybridization in S1Pcko humerus and by immunohistochemistry (IHC) for Scd1 protein in S1Pcko femur.
23749645	0.98	Fads2, Scd1 and Scd2 in Pten null tumors.
	0.95	scd2, fads2 and acsl5 vs. acsl1 ratio, elevated hepatic and circulating vaccenic (18:1n7) and erucic (22:1n9) acids and reduced hepatic and circulating margaric (17:00) and linoleic (18:2n6, LA) acids.
26473289	0.98	Scd2 was down-regulated, whereas the Fads1 and Fads2 transcripts were elevated in Gata4 cKO testes (Tables S3 and S4).
30364153	0.98	Fads2, Scd1, and Scd2.
27424223	0.97	Fads2, Scd1 and Scd2).
31267675	0.97	Fads2 and the stearoyl Co-A desaturases Scd1 and Scd2 in the latter (Figure S1E; Table S1).
19785743	0.96	Fads2, Scd2, Elovl1, and Aldo3) were shifted to smaller polysomes in c-Myc mutant glands, other mRNAs were not affected.
	0.93	Fads2, Scd2 and Elovl1 that are described Myc targets in other systems (, Zeller et al.).
	0.93	Fads2, Scd2, Elovl1 and Aldo3 each shifted to smaller polysomes, with the peaks in fractions 7 to 9 in mutant versus 8 to 10 in WT glands (Figure 4(c), upper panel, open arrow heads).
21079772	0.96	Scd2, Elovl6, Elovl5, Fads2, and Elovl1) showed similar expression patterns to the fatty acid synthesis enzymes (Figure 5B ).
21573029	0.96	Scd2 and Fads2, respectively, along with the elongase Elovl7, which preferentially elongates saturated fatty acids and the phosphatidic acid phosphatase Lpin2.
31105522	0.79	Fads2, HMG-CoA, Acat2, Scd2, and Fads1, and lower levels of Elovl2 and GPx4m+c.
21442273	0.75	FADS2 (Delta-6 desaturase) mRNAs were increased with elevated GH while FAS mRNA was reduced; SCD1 (ste-aroyl-coenzyme A desaturase) and SCD2 mRNA did not significantly differ.
26245716	0.73	Fads2 was also noted in both males and females, with inconsistent elevations in Scd2 (males only) and Fads3 (females only; Fig. 6c,d).