Publication for Scd2 and Insig1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Scd2	stearoyl-Coenzyme A desaturase 2	20250			[link]
mmu	Insig1	insulin induced gene 1	231070

Pubmed ID	Priority	Text
24806461	0.98	Insig1/2Delta/Delta mice (Table S2), including Scd1, Scd2, Fasn, Ldlr, Hmgcs1, Sqle and Lss, demonstrating an inverse relationship between SREBP suppression and activation in ScapDelta/Delta and Insig1/2 Delta/Delta mice, respectively.
25147951	0.98	Scd2, Stard4, Ldlr, Insig-1, and Fdps, which are direct targets of SREBPs and involved in the cholesterol/lipid biosynthetic pathways, are down-regulated in S1Pcko cartilage (Table 2) mirroring that seen in the microarray.
29051053	0.98	insulin-induced gene 1 (INSIG1), mitochondrial citrate transporter (SLC25A1), and stearoyl-CoA desaturase 2 (SCD2) in SCAP KO mice, the proportion of de novo synthesized FAs in the milk decreased by 25%, suggesting that SREBP-dependent pathway is necessary for optimal lipogenesis in the lactating mammary gland.