Publication for Scd2 and Srebf2

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Scd2 stearoyl-Coenzyme A desaturase 2 20250 [link]
mmu Srebf2 sterol regulatory element binding factor 2 20788

Pubmed ID Priority Text
25849048 0.97 SCD2, AGPAT3), metabolism (e.g. LPIN2, LPPR4, CPT1A, SMPD3), and cholesterol homeostasis (e.g. SREBF2, SCAP) and transport (e.g. LPR1, SORL1, ABCA3, LRP8).
31083413 0.97 Srebf2, Fas, Acc2, Scd1, Scd2, Gpam, Dgat1, and Dgat2.
31630534 0.96 SREBP2/SCD2 genes and drives liver fibrosis in e HF-CDAA model.
0.96 SREBP2 and SCD1 and SCD2) in the context of CDAA feeding, whereas other genes remained largely unaffected (Fig. 5).
0.96 SREBP2, normally absent from healthy adult liver, is induced by the HF-CDAA diet and activates SCD2, which in turn mediates profibrogenic effects of the HF supplementation in our model.
0.95 SCD2, previously identified as a direct downstream target gene of the transcription factor SREBP2 was nearly superimposable on that of SREBP2 (but not SREBP1).
0.94 SCD2 and SREBP2 were induced to a considerably lesser degree (P = 0.011 and P = 0.037, respectively), consistent with an attenuated fibrotic response in this model (BALB/c < C57Bl/6; Supplemental Table S7 and Supplemental Fig. S3).



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