Publication for Scd2 and Srebf2
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Scd2 | stearoyl-Coenzyme A desaturase 2 | 20250 | [link] | ||
| mmu | Srebf2 | sterol regulatory element binding factor 2 | 20788 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 25849048 | 0.97 | SCD2, AGPAT3), metabolism (e.g. LPIN2, LPPR4, CPT1A, SMPD3), and cholesterol homeostasis (e.g. SREBF2, SCAP) and transport (e.g. LPR1, SORL1, ABCA3, LRP8). |
| 31083413 | 0.97 | Srebf2, Fas, Acc2, Scd1, Scd2, Gpam, Dgat1, and Dgat2. |
| 31630534 | 0.96 | SREBP2/SCD2 genes and drives liver fibrosis in e HF-CDAA model. |
| 0.96 | SREBP2 and SCD1 and SCD2) in the context of CDAA feeding, whereas other genes remained largely unaffected (Fig. 5). | |
| 0.96 | SREBP2, normally absent from healthy adult liver, is induced by the HF-CDAA diet and activates SCD2, which in turn mediates profibrogenic effects of the HF supplementation in our model. | |
| 0.95 | SCD2, previously identified as a direct downstream target gene of the transcription factor SREBP2 was nearly superimposable on that of SREBP2 (but not SREBP1). | |
| 0.94 | SCD2 and SREBP2 were induced to a considerably lesser degree (P = 0.011 and P = 0.037, respectively), consistent with an attenuated fibrotic response in this model (BALB/c < C57Bl/6; Supplemental Table S7 and Supplemental Fig. S3). |
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