Publication for Cdc42 and Ppp1ca

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Cdc42 cell division cycle 42 12540 [link]
mmu Ppp1ca protein phosphatase 1 catalytic subunit alpha 19045

Pubmed ID Priority Text
28457749 0.98 CDC42/PP1A cascade to control YAP-S397 phosphorylation and nuclear localization.
0.98 CDC42/PP1A signaling axis that governs YAP localization in the incisor TA cells.
0.98 PP1A as an important modulator of YAP phosphorylation downstream of CDC42.
0.98 PP1A itself could potentially be activated by the CDC42 effector, PAK2, and PAK2 activity was reduced in Cdc42cKO laCLs (Figure S5C).
0.98 CDC42 signaling predominantly controls YAP phosphorylation at S397, but not S127, a phenomenon that has been previously shown in Netrin-1-induced PP1A dephosphorylation of YAP.
0.98 CDC42/PP1A signaling axis drives YAP nuclear localization, which promotes proliferation by activating mTOR signaling and inhibits precocious differentiation and apoptosis.
0.95 PP1A and found a significant reduction in pulled-down PP1A (but not PP2A, data not shown) in Cdc42cKO laCL lysates (Figure 6J).
0.94 CDC42 signals through PP1A to regulate YAP S397 phosphorylation and localization
0.86 PP1A may dephosphorylate YAP primarily on S397, we tested whether PP1A binding to YAP was diminished upon Cdc42 deletion.
28891248 0.97 CDC42-PP1A signaling cascade that directs nuclear YAP/TAZ activity in stem cell populations of the mouse incisor, and define convergence on mTORC1 signaling as an important mediator of the proliferation of these cells.



The preparation time of this page was 0.0 [sec].