Publication for Cdc42 and Ppp1ca
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Cdc42 | cell division cycle 42 | 12540 | [link] | ||
| mmu | Ppp1ca | protein phosphatase 1 catalytic subunit alpha | 19045 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 28457749 | 0.98 | CDC42/PP1A cascade to control YAP-S397 phosphorylation and nuclear localization. |
| 0.98 | CDC42/PP1A signaling axis that governs YAP localization in the incisor TA cells. | |
| 0.98 | PP1A as an important modulator of YAP phosphorylation downstream of CDC42. | |
| 0.98 | PP1A itself could potentially be activated by the CDC42 effector, PAK2, and PAK2 activity was reduced in Cdc42cKO laCLs (Figure S5C). | |
| 0.98 | CDC42 signaling predominantly controls YAP phosphorylation at S397, but not S127, a phenomenon that has been previously shown in Netrin-1-induced PP1A dephosphorylation of YAP. | |
| 0.98 | CDC42/PP1A signaling axis drives YAP nuclear localization, which promotes proliferation by activating mTOR signaling and inhibits precocious differentiation and apoptosis. | |
| 0.95 | PP1A and found a significant reduction in pulled-down PP1A (but not PP2A, data not shown) in Cdc42cKO laCL lysates (Figure 6J). | |
| 0.94 | CDC42 signals through PP1A to regulate YAP S397 phosphorylation and localization | |
| 0.86 | PP1A may dephosphorylate YAP primarily on S397, we tested whether PP1A binding to YAP was diminished upon Cdc42 deletion. | |
| 28891248 | 0.97 | CDC42-PP1A signaling cascade that directs nuclear YAP/TAZ activity in stem cell populations of the mouse incisor, and define convergence on mTORC1 signaling as an important mediator of the proliferation of these cells. |
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