Publication for AFM and GC

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	AFM	afamin	173			[link]
hsa	GC	GC vitamin D binding protein	2638

Pubmed ID	Priority	Text
29875736	0.98	vitamin D-binding protein (VDBP), also known as group-specific component of serum (Gc-globulin), is a member of the albumin, alpha-fetoprotein, and alpha-albumin/afamin gene family and the major plasma carrier protein of vitamin D and its metabolites.
24089082	0.97	Afamin, or alpha-albumin, is the fourth member of the albumin family, which includes albumin, alpha-fetoprotein, and vitamin D-binding protein.
25208973	0.97	Afamin was discovered in 1994 as the fourth member of the human albumin gene family, which includes human serum albumin, alpha-fetoprotein and vitamin D-binding protein.
24707212	0.96	AFM and VDBP are grouped in the same superfamily, they show differential nucleotide composition suggesting variation in their biological functions compared to the other members of albumin superfamily.
	0.96	AFM, and VDBP, exhibit sequence and structural similarities.
	0.95	AFM, AFP, and VDBP are 4%, 3%, 4%, and 4%, respectively.
30623593	0.96	Vitamin D-binding protein (2.4-fold), Ig kappa chain V-II region Cum (2.4-fold), Isoform 2 of Eukaryotic translation initiation factor 2-alpha kinase 4 (1.8-fold), Ig alpha-1 chain C region (1.7-fold), and Afamin (1.5-fold) (Table 1).
	0.94	Afamin (5.4-fold), Apolipoprotein A-I (4.9-fold), Isoform 3 of Vitamin D-binding protein (4.3-fold), Complement C1r subcomponent (4.3-fold), and Angiotensinogen (4.1-fold) (Table 2).
	0.91	Vitamin D-binding protein in pancreatic cancer,38 and Afamin in ovarian cancer.39 Interestingly, here, we report that these proteins are present in exosomes from African Americans with PCa.
23101585	0.96	Vitamin D Binding-Protein (VitDBP), Afamin, Fibronectin, Leucine-rich alpha-2 glycoprotein 1 (LRG1), Galectin 3 Binding-Protein, C-Reactive Protein and Ferritin Light-chain.
	0.95	Vitamin D Binding-Protein, Afamin and Fibronectin).
24339887	0.96	Afamin (a-albumin, a1T-glycoprotein) is the newest member of the albumin family comprising albumin, a-fetoprotein, and vitamin D binding protein.
	0.95	afamin, leucine-rich alpha-2-glycoprotein, ceruloplasmin, alpha-1-microgolbulin, hemopexin, apolipoprotein A-I, complement C3, vitamin D-binding protein, beta-2-microglobulin, and retinol-binding protein 4.
26902720	0.96	AFM, alpha-fetoprotein (AFP), and vitamin D binding protein (VDBP), all present in blood at different concentrations.
	0.52	AFM, human afamin; AFP, human alpha-fetoprotein; VDBP, mouse vitamin D binding protein.
21136797	0.96	Afamin is a vitamin E binding protein which together with alpha-fetoprotein, serum albumin, and vitamin D binding protein belongs to albumin gene family and is predominantly expressed in liver.
31057599	0.96	vitamin D-binding protein (Gc-globulin) and afamin (alpha-albumin) is only ca.
23844025	0.95	Vitamin D-binding protein (VDBP, spot no: 1-3, 29 and 30) belongs to the albumin superfamily of binding proteins that includes albumin, alpha-albumin, and alpha-fetoprotein.
23849470	0.94	VTDB and kininogen-1 (KNG1) were found overexpressed, whilst S10A9 and afamin (AFAM) were significantly down-regulated.
16648359	0.89	vitamin D-binding protein (hDBP) gene is a member of a cluster that includes albumin, alpha-fetoprotein and alpha-albumin genes.
19908921	0.84	vitamin D binding protein, histidine rich glycoprotein and afamin (Table 2).
27913752	0.83	vitamin D-binding protein (VTDB) and alpha-albumin (afamin).
28680266	0.80	vitamin D-binding protein, and afamin.
	0.56	vitamin D-binding protein and afamin.
28855568	0.80	VDBP were selected based on 2-D DIGE analysis (Table 1, Fig. 5) and APOL1, IGFBP-ALS, afamin, IGFBP 3, lumican and ECM1 were selected based on iTRAQ LC-MS/MS analysis as rGH biomarkers (Table 1, Fig. 4).
	0.59	vitamin D-binding protein, afamin, insulin-like growth factor-binding protein-3, insulin-like growth factor-binding protein-ALS, lumican and extracellular matrix proteins 1 were identified.
32019136	0.71	alpha-albumin (afamin) and vitamin D-binding protein (VTDB).
32190302	0.71	alpha-albumin) and vitamin D binding protein and these proteins tend to be homologous, that is, all members of the albuminoid superfamily of proteins are suitably capable of ligand binding and transport, as they possess highly conserved intron/exon organization.
24798303	0.69	vitamin D binding protein and alpha-albumin.
25349266	0.61	vitamin D-binding protein (official gene symbol: GC, group-specific component), albumin (ALB), alpha-fetoprotein (AFP), and afamin (AFM).