Publication for Ldlr and Dhcr24
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Ldlr | low density lipoprotein receptor | 16835 | [link] | ||
| mmu | Dhcr24 | 24-dehydrocholesterol reductase | 74754 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 22855714 | 0.98 | Dhcr24, Sqle and Idi1) and in the uptake of extracellular cholesterol (Ldlr) (Fig. 5B). |
| 23021221 | 0.98 | Dhcr24, were down-regulated by the HCHF diet, especially in LDLR KO mice (Figure 2B), with Dhcr24 being the most suppressed transcript among the entire set of transcripts evaluated. |
| 24498295 | 0.98 | Dhcr24 and Akr1d1) and a receptor gene for cholesterol recovery from peripheral tissue (Ldlr) were found to be up-regulated in the presence of ethanol and the polyphenols. |
| 31922003 | 0.98 | DHCR24, HMGCR, and LDLR, as well as fatty acid metabolism genes SREBP-1c, FASN, ACC-1, and SCD-1 after PMFE treatment (Fig. 1E). |
| 32111832 | 0.98 | Dhcr24, Pcsk9, and Ldlr (Fig. 4c). |
| 26938916 | 0.97 | DHCR24, HMGCS1, LDLR, NSDHL, SC4MOL, SREBF2; S4F Table). |
| 0.96 | DHCR24, HMGCS1, LDLR, NSDHL, SREBF2, SC4MOL) mostly differ with those in Bahd1-KO murine placentas (e.g. Apoc3, Atp8b1, Cyp11A1, Insig2, Osbpl5, Pbx1, VldlR). | |
| 29632203 | 0.96 | Dhcr24, Hmgcr, and Ldlr) while GW3965 and T0901317 activate Fasn and Srebf1 (Fig. 5B). |
| 29738536 | 0.95 | Dhcr24 (24-Dehydrocholesterol Reductase), Hmgcs (HMG-CoA Synthase), Ldlr (Low Density Lipoprotein Receptor), Fdps (Farnesyl Diphosphate Synthase), and Sqs (Squalene Synthase) and found that all were dose dependently upregulated by pravastatin (Fig 4C) as well as simvastatin (S4A Fig). |
| 25799309 | 0.87 | Dhcr24, Nsdhl, Fdps, Sc4mol, Fdft1 and Tm7sf2), cholesterol transport and uptake (e.g., Cd36, Apoa4 and Ldlr), cholesterol homeostasis (e.g., Fabp4, Apoa4, Pcsk9 and Ldlr), triglyceride synthesis (Ces3, Ppap2a, Dgat2, Ppap2c and Pcsk9) and triacylglycerol catabolism (Lpl and Gk2) (Fig. 4A, Fig. 5E, F and S7-S8 Tables), indicating that the decreased expression of these hepatic genes involved in cholesterol and triglyceride metabolism might be responsible, or contribute to the decreased cholesterol and triglyceride levels observed in Rm155LG/Alb-Cre transgenic mice. |
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