Publication for Ldlr and Sc5d

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Ldlr	low density lipoprotein receptor	16835			[link]
mmu	Sc5d	sterol-C5-desaturase	235293

Pubmed ID	Priority	Text
27168937	0.97	ldlr, lss, mvk, sc4mol, sc5dl, sqle) that Schmidt et al. (2009) identified as differently expressed in response to conditional knockout of por in mice, a cytochrome P450 that is essential for steroidogenesis (Fluck et al. 2004), were coordinately upregulated in our study at 22-24 DPA.
	0.90	ldlr, lss, mvk, pmvk, insig1, sc4mol, sc5dl, sqle) (Fig. 12I-L).
25799309	0.87	Sc5d, Hmgcr, Sqle, Cnbp, Dhcr24, Nsdhl, Fdps, Sc4mol, Fdft1 and Tm7sf2), cholesterol transport and uptake (e.g., Cd36, Apoa4 and Ldlr), cholesterol homeostasis (e.g., Fabp4, Apoa4, Pcsk9 and Ldlr), triglyceride synthesis (Ces3, Ppap2a, Dgat2, Ppap2c and Pcsk9) and triacylglycerol catabolism (Lpl and Gk2) (Fig. 4A, Fig. 5E, F and S7-S8 Tables), indicating that the decreased expression of these hepatic genes involved in cholesterol and triglyceride metabolism might be responsible, or contribute to the decreased cholesterol and triglyceride levels observed in Rm155LG/Alb-Cre transgenic mice.