Publication for Ldlr and Scd2

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Ldlr low density lipoprotein receptor 16835 [link]
mmu Scd2 stearoyl-Coenzyme A desaturase 2 20250

Pubmed ID Priority Text
25147951 0.98 Scd2, Stard4, Ldlr, Insig-1, and Fdps, which are direct targets of SREBPs and involved in the cholesterol/lipid biosynthetic pathways, are down-regulated in S1Pcko cartilage (Table 2) mirroring that seen in the microarray.
0.97 Scd2, Ldlr, Fads2, and Fdps genes at the RNA level in the humerus of S1Pcko mice (Fig. 8).
0.93 Scd2, Ldlr, Fads2, and Fdps genes at the RNA level, shown by in situ hybridization in S1Pcko humerus and by immunohistochemistry (IHC) for Scd1 protein in S1Pcko femur.
28515432 0.98 Scd2, Fabp5, Thrsp and Hmgcr), lipid endocytosis (Ldlr), and lipid esterification (Dgat2, Mogat2 and Plin2).
0.93 Scd2, Hmgcr, Ldlr, Dgat2, Mogat2, Plin2, and Fabp5) in the HS mice were significantly decreased (P < 0.05 or P < 0.01, Fig. 5B), and the expression of Acsl6 in the HS mice was significantly increased (P < 0.01, Fig. 5B).
23823481 0.98 Scd2, Acaca, Fasn, Dgat1, Dgat2) and lipid uptake (Pltp, Vldlr, Ldlr, Ldrap1, Lpl,) were increased in LOKO fat depots.
24806461 0.98 Scd2, Fasn, Ldlr, Hmgcs1, Sqle and Lss, demonstrating an inverse relationship between SREBP suppression and activation in ScapDelta/Delta and Insig1/2 Delta/Delta mice, respectively.



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