Publication for Ldlr and Acaca
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Ldlr | low density lipoprotein receptor | 16835 | [link] | ||
| mmu | Acaca | acetyl-Coenzyme A carboxylase alpha | 107476 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 26867493 | 0.97 | ACC1 and LDLR) in WT mice and this was prevented in KO mice. |
| 0.95 | ACC1 (Fig.2H), and LDLR (Fig.2I) in the livers of WT mice and not in miR-155 KO mice. | |
| 31749969 | 0.97 | ACCalpha were significantly lower in IL-1alpha KO compared with Loxp mice (figure 6A), with similar levels of DGAT, LXR, Srebpf-1c, ChREBP, HMGCR, Cyp7a and LDLR (Fig. 6A and online supplementary fig. S1). |
| 0.78 | ACCalpha), diacylglycerol acyltransferase (DGAT), the primary regulators of DNL including liver X receptors (LXR), sterol regulatory element-binding protein-1c (Srebpf-1c) and carbohydrate response element binding protein (ChREBP), and cholesterol metabolism related genes such as 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), cholesterol 7 alpha-hydroxylase (Cyp7a) and LDL receptor (LDLR). | |
| 20649970 | 0.97 | ACC1, FAS, HSL, LDLR and COX 4 were also up-regulated in the BAT of FSP27-/- mice, whereas the mRNA levels for UCP3, CPT1, LPL and adipsin were down-regulated in the BAT of FSP27-deficient mice (Figure 4B). |
| 24438079 | 0.97 | acetyl-CoA carboxylase (ACC; Acaca) but not stearoyl-CoA desaturase 1 (SCD1; Scd1) were elevated in HFSC- compared to HFC-fed LDLR-/- mice after 16 weeks of treatment (Figure 5A-C). |
| 29264458 | 0.97 | Acaca, Ldlr, and Cidec). |
| 26318157 | 0.95 | ACCa and FASN, two key enzymes in fatty acid synthesis, were significantly decreased, while expression levels of LDLR were not changed (Fig. 5A). |
| 30674978 | 0.95 | Ldlr-/-, mice, treatment with pNAPE-EcN also increased expression of Aco and Cpt1a, as well as decreased hepatic expression of Cd36, Acc1, and Acc2. |
| 25072708 | 0.93 | ACC-1, FAS are the target genes of SREBP-1 pathway, and HMGR and LDLR are the target genes of SREBP-2. |
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