Publication for Hmgcs2 and Acot1
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Hmgcs2 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 | 15360 | [link] | ||
| mmu | Acot1 | acyl-CoA thioesterase 1 | 26897 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 30765765 | 0.98 | Hmgcs2, Bdh2, Acot1, and Acot2. |
| 0.97 | Hmgcs2, Acot1 and liver Hmgcr associated significantly with the abundance of several Bifidobacterium species and Bacilli species. | |
| 0.94 | Hmgcs2, Cyp1a1, Cldn8, and Acot1 in the ileal mucosa and Hmgcr in the liver (Fig. 5). | |
| 22698140 | 0.98 | Hmgcs2, Acot1, Acot2, Mcad, and Lcad, were significantly upregulated in the duodenum of the Mgat2-deficient mice (Figure 7). |
| 26977393 | 0.98 | Acot1 and Hmgcs2 (by more than 7-fold) which are both regulated by activation of PPARalpha. |
| 26861690 | 0.97 | Hmgcs2, Acot1, Acot2, Pdk4, Acaa1b, Cpt1, Fabp1, and Acadl) were significantly up-regulated in the intestine of both A/J (obesity-resistant) and C57BL/6J (obesity-prone) mice fed with high fat diet. |
| 0.80 | Hmgcs2, Acot1, Acaa1b and Acadl were linearly responsive and up-regulated in the proximal and middle sections; (III) in the proximal and middle sections, the expression of Pdk4 was up-regulated and displayed a logarithmic response; (IV) Acot2 was up-regulated and linearly responsive in the proximal section only. | |
| 24834104 | 0.97 | Acot1 expression was upregulated in the FO group and also Hmgcs2 (mitochondrial rate limiting enzyme in ketone body formation) was upregulated in the FO group but not appreciably by KO (Figure 2, see "Additional metabolic pathways" and "Mitochondrial pathways"), suggesting a more potent PPARalpha-activation by FO. |
| 23226270 | 0.96 | HMGCS2, HSD17B10, UCP3, EHHADH, CPT1A, DCTN6, PIGL, SULT1A1, SLC27A2, MLYCD and ACOT1 were increased; LPCAT1 and CD74 were repressed. |
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