Publication for Hmgcr and Sc5d

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	15357			[link]
mmu	Sc5d	sterol-C5-desaturase	235293

Pubmed ID	Priority	Text
19691840	0.98	Hmgcr, Sqle, Lss, and Sc5d) were up-regulated (Table 2 and 3); however, the ratio of lathosterol to cholesterol did not confirm increased cholesterol biosynthesis (Figure 1B, pale grey boxes).
30069000	0.98	Hmgcr, Hmgcs1, Hsd17b7, Idi1, Lss, Mvd, Mvk, Msmo1, Nsdhl, Pmvk, Sc5d, Sqle, and Tm7sf2 were significantly decreased in HFD livers.
28150810	0.97	Hmgcr, Mvk, Fdps, Sqle, Lss, Nsdhl, Sc5d, and Dhcr24.
28328977	0.97	Sc5d, Hmgcr, Cyp2d9, etc.) and acute inflammatory response (CRP, C9, etc.) (S4A and S4B Fig).
28591574	0.95	HMGCR and lower SC5D in the KO glands suggests an accumulation of cholesterol precursors but not necessarily cholesterol itself.
25799309	0.87	Sc5d, Hmgcr, Sqle, Cnbp, Dhcr24, Nsdhl, Fdps, Sc4mol, Fdft1 and Tm7sf2), cholesterol transport and uptake (e.g., Cd36, Apoa4 and Ldlr), cholesterol homeostasis (e.g., Fabp4, Apoa4, Pcsk9 and Ldlr), triglyceride synthesis (Ces3, Ppap2a, Dgat2, Ppap2c and Pcsk9) and triacylglycerol catabolism (Lpl and Gk2) (Fig. 4A, Fig. 5E, F and S7-S8 Tables), indicating that the decreased expression of these hepatic genes involved in cholesterol and triglyceride metabolism might be responsible, or contribute to the decreased cholesterol and triglyceride levels observed in Rm155LG/Alb-Cre transgenic mice.