Publication for Hmgcr and Nsdhl

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 15357 [link]
mmu Nsdhl NAD(P) dependent steroid dehydrogenase-like 18194

Pubmed ID Priority Text
19183246 0.98 NSDHL and SQLE are members of the mevalonate pathway downstream of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and represent potent therapeutic targets for cholesterol-lowering agents.
22252456 0.98 Hmgcr, Pmvk, Mvd, Fdps, Nsdhl, Idi1, Sc4mol, Cyp51, and Dhcr7).
27878435 0.98 HMGCR, HSD3B7, HMGCS1, LSS, FDFT1, DHCR7, HSD17B7, NSDHL, DHCR24, FDPS, SIGMAR1, SQLE, MVK, that are expressed in the lens.
30069000 0.98 Hmgcr, Hmgcs1, Hsd17b7, Idi1, Lss, Mvd, Mvk, Msmo1, Nsdhl, Pmvk, Sc5d, Sqle, and Tm7sf2 were significantly decreased in HFD livers.
28150810 0.97 Hmgcr, Mvk, Fdps, Sqle, Lss, Nsdhl, Sc5d, and Dhcr24.
22912762 0.96 NAD(P)H steroid dehydrogenase-like protein (Nsdhl)) were significantly decreased in the Mig-6d/d mice compared to Mig-6f/f mice while others (3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr)) were not.
20303728 0.93 NAD(P)-dependent steroid dehydrogenase-like (Nsdhl), 3-hydroxy-3-methylglutaryl coenzyme A reductase (Hmgcr), were also decreased in the HFLD-fed mice.
25799309 0.87 Hmgcr, Sqle, Cnbp, Dhcr24, Nsdhl, Fdps, Sc4mol, Fdft1 and Tm7sf2), cholesterol transport and uptake (e.g., Cd36, Apoa4 and Ldlr), cholesterol homeostasis (e.g., Fabp4, Apoa4, Pcsk9 and Ldlr), triglyceride synthesis (Ces3, Ppap2a, Dgat2, Ppap2c and Pcsk9) and triacylglycerol catabolism (Lpl and Gk2) (Fig. 4A, Fig. 5E, F and S7-S8 Tables), indicating that the decreased expression of these hepatic genes involved in cholesterol and triglyceride metabolism might be responsible, or contribute to the decreased cholesterol and triglyceride levels observed in Rm155LG/Alb-Cre transgenic mice.



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