Publication for H2ax and Top2a

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	H2ax	H2A.X variant histone	15270			[link]
mmu	Top2a	topoisomerase (DNA) II alpha	21973

Pubmed ID	Priority	Text
27104530	0.98	Topoisomerase (DNA) II Alpha (TOP2-A), H2A Histone Family, Member X (H2AFX), Regulator of chromosome condensation 1 (RCC1) and Retinoblastoma Binding Protein 4 (RBBP4) have been previously identified as H3K4me3-associated in mouse embryonic stem cells.
29335648	0.97	Top2a and gamma-H2AX localization (Fig. 2d-g and Supplementary Fig. 3), suggesting an indirect influence of Aire on accessibility at these loci.
	0.91	Top2a) and gamma-H2AX deposition (Fig. 2d-g and Supplementary Fig. 2g,3), further supporting their enhancer potential.
30893341	0.93	Top2a, and Smc3 in early spermatocytes; Sycp1/2/3 and H2afx in spermatocytes; Acrv1, Izumo1, and Catsper3/4 in round spermatids; and Prm3, Izumo3, and Tssk6 in elongated spermatids (Figs 3, S5 & S6, S2 Table).
28135252	0.88	gammaH2AX co-localized highly preferentially with Aire at super-enhancer regions (Fig. 5a, b and Supplementary Fig. 6), while the distribution of TOP2A was more dispersed, spreading beyond super-enhancers locally and far-distally (Fig. 5a, b and Supplementary Fig. 6).
	0.73	TOP2A peaks showed co-association with Aire, RNA-PolII, gammaH2AX and TOP1, but almost exclusively at the TSSs (Fig. 5f).