Publication for Gfi1b and Klf1

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Gfi1b	growth factor independent 1B	14582			[link]
mmu	Klf1	Kruppel-like factor 1 (erythroid)	16596

Pubmed ID	Priority	Text
21695229	0.99	Gfi-1b, EpoR, and Klf1 (Figure 3C and Figure 4).
	0.98	Gfi-1b, Klf1, and EpoR are significantly downregulated (Figure 3C).
	0.97	Gfi-1b, the erythropoietin receptor (EpoR), and the erythroid kruppel-like factor Klf1 promote erythroid differentiation.
	0.67	Gfi1b, and EpoR are transcribed from the negative strand (right to left), whereas Sfpi1 (PU.1) and Klf1 are expressed in the sense direction (left to right).
25564442	0.99	Gfi1b, Pu.1/Sfpi1 and Klf1 was down-regulated in Gata1&2KO endothelial cells (Fig6D), implying that Gata1 and/or 2 is required for the induction of the hematopoietic transcription factor network that enables the emergence of HS/PCs from hemogenic endothelium.
	0.98	Klf1, Gfi1b).
22412390	0.99	Gfi1b Klf1 and Klf3, are up-regulated in CD34- cells (Figure 1).
29300724	0.98	Gfi1b and Klf1) were downregulated in wild type CD31high CMPs compared to wild type CD31low CMPs, reflecting the megakaryocytic/erythroid lineage commitment which accompanies CD31 downregulation in the CMP compartment and demonstrating that CD31low and CD31high CMPs represent transcriptionally distinct progenitor subsets.
	0.93	Gfi1b, Klf1 and Gata2, plus the megakaryocytic/erythroid lineage markers Itga2b, Pf4 and Epor (S7R Fig), were all expressed at comparable levels in Runx1-del/del CD31low CMPs to CD31high CMPs (of all genotypes).
29861167	0.98	KLF1, NFE2, and GFI1B genes and their regulons, was the most stable core of response across all hemogenic subsets.
	0.86	KLF1, and GFI1B regulons were not active, while, SOX17 and SOX18 regulons displayed slight increases in their regulon-level signal in non-HE.
31996238	0.98	Gfi1b, Klf1, and Tal1 encode transcription factors which are known to be critically involved in erythropoiesis.
	0.96	Gfi1b, Tal1, Klf1, Epor, and Cldn13.
21057528	0.98	Gfi-1b and eklf.
24752325	0.98	Gfi1b, Klf1, and Tal1, the latter three confirmed by RT-PCR analysis (Figure 8).
24800817	0.98	KLF1, remained similarly regulated during development in Gfi1b knockout fetal liver cells and wt controls (Figure 8A).
27888632	0.98	KLF1 (5.0-fold, p<0.0001), GFI1B (2.5-fold, p<0.0001), LMO2 (1.7-fold, p<0.001) and TAL1 (2.3-fold, p<0.0001) were downregulated in CD34+ CB cells constitutively expressing VENTX.
29968757	0.98	Gfi1b Klf1, and Ikzf1, known to maintain embryonic blood cells were found in the synergistic transcriptional core of the embryonic primitive erythrocyte subpopulation (Supplementary Data 1).
30206223	0.98	Klf1, Gata1 and Gfi1b.
24711581	0.97	Gfi-1b-/- progenitors had initiated the erythroid program as they expressed many lineage-restricted genes, including Klf1/Eklf and Erythropoietin receptor.
27713415	0.97	Klf1 (Fig. 3e), which are known to regulate primitive erythropoiesis during embryogenesis, as well as Gfi1b (Fig. 3e).
29472540	0.97	KLF1, and GFI1b.
24035353	0.96	Gfi1b, Nfia and Klf1), and negatively correlates with a lymphomyeloid module (characterized by Flt3, Sell, Cebpa and Notch1).
30814124	0.96	Klf1, Gfi1b, or Runx1 were unaffected (Fig 5G).
23159334	0.95	eklf and gfi-1b) or increased transcript level (scl, hba) at the 5' end, whereas the levels of 3' transcripts were significantly reduced for all tested erythroid genes (Fig. 6A).
27207878	0.95	Klf1, Gfi1b and Gata1 expression, characteristic of erythroid lineage progenitors, similar to Clusters 1-6 in the original study (Figure 1c in).
23675896	0.94	Klf1, Gfi1b) are known to play different roles in the primitive versus definitive erythroid lineages; thus the scores of individual genes are expected to vary across the lineages and likely reflect the underlying biology.