Publication for Gfi1b and Itga2b

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Gfi1b	growth factor independent 1B	14582			[link]
mmu	Itga2b	integrin alpha 2b	16399

Pubmed ID	Priority	Text
30894540	0.98	Gfi1b WT/KO CD41+/CD9+ HSCs, MKs, and CD41low/CD9lowHSCs showed that many genes, which were differentially expressed between WT and Gfi1b-deficient cells, belong to previously published sets of genes involved in Wnt/beta-catenin signaling (Fig. 6a, b).
	0.98	Gfi1b WT CD41+/CD9+ HSCs and CD41low/CD9lowHSCs and a set of genes down-regulated upon activation of canonical Wnt signaling, was enriched in Gfi1b KO MKs (Fig. 6c).
	0.88	CD41-/CD9- HSCs and were also co-occupied by Gfi1b and beta-catenin or also by LSD1 (Fig. 6d, Supplementary Table 2, Supplementary Fig. 3).
	0.81	Itga2b (CD41) and Itgb3 (CD61), are up-regulated in Gfi1b-deficient HSCs.
24800817	0.98	CD41/61), already described as Gfi1b effectors in HSCs and several other megakaryocyte/platelet specific genes such as Gp1bb (CD42C), Timp3 or Pf4 showed increased expression in Gfi1b deficient cells (Figure 5B).
24095001	0.97	Gfi1b transduced hemogenic endothelial cells initiated morphological changes akin to the formation of hematopoietic progeny, forming round cells that express CD41.
	0.87	Gfi1b resulted in the generation of CD41 expressing adherent cells that maintained endothelial marker expression, which could only generate clonogenic progeny upon disaggregation.
29300724	0.97	Gfi1b was expressed in all CD41- CD150+ MEPs and CMPs, although the Gfi1b-GFP median fluorescence intensity (MFI) was decreased in some CD31high CMPs (S4F Fig).
	0.91	Gfi1b, Klf1 and Gata2, plus the megakaryocytic/erythroid lineage markers Itga2b, Pf4 and Epor (S7R Fig), were all expressed at comparable levels in Runx1-del/del CD31low CMPs to CD31high CMPs (of all genotypes).
24035353	0.97	CD41, CD150, Gata1, vWF, Mpl and Gfi1b, maintains high correlation in single HSCs (Figure 6A).
24326267	0.97	CD41, they expressed higher levels of Runx1 and its direct targets, upregulated Myb, Gfi1b and Itgb3 (CD61 (ref.)), and further downregulated Kdr, reflecting progressive locking in of the haematopoietic programme and development into fully determined CD45+ HPCs (E9.5 and E10.5, Fig. 5b-d and Supplementary Fig. S4b).
28973433	0.97	CD41+, CD45- progenitors expressed higher levels of Tal1, Gata1, Gata2, Runx1, Gfi1, Gfi1b, and Nfe2, whereas CD41+, CD45+ cells exhibited higher levels of Spi1 and Cebpb (Supplementary Figure S1).
22554697	0.96	Itga2b, Hexim 2, Tmem56, Runx1, Mettl8, Gfi1b, Gata1) and 3 out of 10 of our bound and negatively-correlated (Camsap1l1, Casp4, Sbf2) showed differential expression, thus demonstrating dependence on sustained Runx1 expression for a high proportion of the Runx1 candidate target genes identified in our study.
25252941	0.95	CD41+ cKithi population (including Runx1, Myb, Gfi1b, Ikaros and PU.1) (Fig. 4D).
29328910	0.95	Gfi1b, and Gata2; and of the differentiation markers Itga2b, Cd34, and Cd48 was enhanced in CD41+ LT-HSCs (but not in CD41- LT-HSCs) from beta-glucan-treated mice, as compared to CD41+ LT-HSCs from PBS control-treated mice (Figures 3D and 3E).