Publication for Gabra1 and Gabra2

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
mmu	Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	14394			[link]
mmu	Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	14395

Pubmed ID	Priority	Text
26469128	0.98	Gabra1 and Gabra2, but not Gabra3 subunit genes in neurons.
	0.98	Gabra1 and Gabra2 promoters, respectively, containing the mutated Sp4 motif (P < 0.001 for all, Fig. 3).
	0.98	Gabra1 and Gabra2, but not Gabra3, subunit genes are regulated by the neuron-specific transcription factor Sp4.
	0.98	Gabra1 and Gabra2 in neurons.
	0.98	Gabra1 and Gabra2, are transcriptionally regulated by Sp4 in neurons, indicating that Sp4's control over GABAA receptor expression is sustained throughout the postnatal life of the animal.
	0.97	Gabra1 (GABAA-alpha1) and Gabra2 (GABAA-alpha2), but not Gabra3 (GABAA-alpha3) subunit genes.
	0.97	Gabra1 and Gabra2 promoters are conserved among mice, rats, and humans.
	0.97	Gabra1, Gabra2, and Gabra3 (* P < 0.05 when compared with controls; N = 3).
	0.96	Gabra1 and Gabra2 with Sp4.
	0.96	Gabra1 and Gabra2 but not Gabra3 subunit genes of GABAA receptors.
	0.96	Gabra1 and Gabra2 promoters from mice, rats, and humans showed conserved Sp binding sites (boxed and underlined).
	0.95	Gabra1 (GABAA alpha1), Gabra2 (GABAA alpha2), and Gabra3 (GABAA alpha3) are transcriptionally regulated by the same transcription factor, Sp4, as some of the key excitatory neurotransmitter receptor subunit genes.
	0.95	Gabra1, and Gabra2 that were significantly above those treated with shRNA and KCl but without over-expression (P < 0.001, P < 0.01, and P < 0.01, respectively, when compared with shRNA-plus-KCl).
	0.95	Gabra1, and Gabra2, respectively (P < 0.01, P < 0.001, and P < 0.05, respectively; Fig. 5C).
	0.94	Gabra1, and Gabra2 mRNA levels in primary neurons, but not of Gabra3.
	0.94	Gabra1, and Gabra2 transcript levels, but not that of Gabra3.
	0.93	Gabra1 and Gabra2 to 210% and 293%, respectively (P < 0.001 for all, Fig. 5C).
	0.91	Gabra1 and Gabra2 mRNA levels, respectively (P < 0.01 for both, Fig. 4C).
	0.91	Gabra1 and Gabra2 resulted in a significant decrease in luciferase activity as compared to the wild type controls.
	0.91	Gabra1, and Gabra2 were significantly down-regulated, but not that of Gabra3 (* P < 0.05; ** P < 0.01; X = non-significant when compared to controls; N = 3).
	0.86	Gabra1, and Gabra2 transcript levels significantly above those with Sp4 shRNA alone (P < 0.05 for all), and these values were not significantly different from those of controls (Fig. 4C).
	0.85	Gabra1 and Gabra2, it has not been characterized previously.
	0.82	Gabra1 and Gabra2 promoter fragments, but failed to do so with the Gabra3 promoter.
	0.81	Gabra1 and Gabra2 transcript levels but not that of Gabra3.
	0.76	Gabra1 and Gabra2 promoters
	0.69	Gabra1, and Gabra2 transcripts from being down-regulated by Sp4 shRNA, but this treatment had no effect on Gaba3 (+ P < 0.05; X = non-significant when compared to shRNA alone; N = 3).
	0.66	Gabra1, and Gabra2 transcript levels to 158%, 164%, and 152%, respectively (P < 0.05 for all).
	0.66	Gabra1, and Gabra2 transcripts that was significantly higher than that of shRNA + KCl, although it had no effect on that of Gabra3 ( = P < 0.01; = P < 0.001; X = non-significant when compared to shRNA + KCl; N = 3).
	0.55	Gabra1, and Gabra2 with TTX.
	0.53	Gabra1, Gabra2, and Gabra3 by means of multiple molecular and biochemical approaches, including in silico analysis, electrophoretic mobility shift and supershift assays, ChIP, RNA interference, over-expression, functional assays, and western blots in rodent primary cortical neurons.
22506031	0.98	Gabra1, Gabra2, Gabra5, Gabra3, Gabrb1, Gabrb2, Gabrb3, Gabrg1, and Gabrg2 (Figure S4).
	0.96	Gabra1, Gabra2, Gabra5, Gabrb2, Gabrb3, and Gabrg2, have remarkably high levels of variation in expression among both inbred strains of mice and normal human populations.
	0.81	Gabra1, Gabra6, Gabra3, and Gabrb2 (mouse) and GABRA2, GABRB1, and GABRB2 (human).
23475113	0.97	GABAA-alpha1, -alpha3, and -beta2 subunit genes (GABRA1, GABRA2 and GABRB2) were blocked by chronic intra-NAc MS-275 infusion (Fig. 4a).
	0.73	GABRA1, F2,16 = 4.902, P = 0.0243; GABRA2, F2,15 = 3.910, P = 0.0468; GABRA3, F2,16 = 10.77, P = 0.0015; GABRB3, F2,15 = 14.83, P = 0.0004; Oct-4, F2,13 = 1.365, P = 0.2954) was observed.
30984232	0.97	Gabra2 mRNA, the transcript levels of several major GABA-A receptor alpha subunits (Gabra1, Gabra3, Gabra5) were also significantly reduced in striatum of Gabra2B6J/B6J mice relative to the Gabra2KI/KI mice (Figure 4).
	0.97	Gabra1 subunit, are observed in the cortex and striatum of B6J allele mice which harbor a naturally occuring intronic deletion resulting in decreased Gabra2 expression.
32188872	0.97	Gabra1, Gabra 2, and Glra2) genes were deregulated (Supplementary Fig. 1a,b).
16772024	0.96	Gabra1 and Gabra2) showed significant differences in the expression between the strains.
	0.92	Gabra1 and Gabra2 subunits showed opposite profiles in C57BL/6J and DBA/2J mice.
26571461	0.96	Gabra2 transcripts in NONO-deficient neurons (P = 0.0020), but unchanged transcript levels for the other postsynaptic markers collybistin (Arhgef9) and Gabra1 (Supplementary Fig. 12).
28970527	0.96	Gabra1 and/or Gabra2, were detected in all sequenced neurons with higher levels in taste neurons.
30097601	0.92	Gabra1, Gabra2, and Gabrb2 were found to be differentially expressed at 1 W; Gabra3 and Gabrb1 were still differentially expressed at 3 W; and Gabra2 and Gabra3 were consistently differentially expressed between the efferent and afferent nerve fibres during development.
29163035	0.91	Gabra1, Gabra2, Gabrg1 and Gabrg2).
31711477	0.91	GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, NR1H4, CHRM1, SLC6A2, SLC6A3, SLC6A4, CYP3A4, DRD1, DRD2, OPRD1, OPRM1, HCRTR1, HTR2A,etc.
30087324	0.83	GABAAR alpha1 and alpha2 subunits, and related inhibitory synaptic proteins in Gabra2-1 mice.
30013074	0.76	Gabra1, Gabra2, and Gabra5 in the KO cerebrum; in contrast, there were significant upregulation for Gabrd, but downregulations for Gabra1, Gabra2, Gabra5 and Gabra6 in the KO cerebellum (Fig. 5j, k, Supplementary Table S3).