Publication for Flg and Flg2
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Flg | filaggrin | 14246 | [link] | ||
| mmu | Flg2 | filaggrin family member 2 | 229574 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 25695600 | 0.98 | Filaggrin-related proteins, including filaggrin2, trichohyalin and cornulin, are also enriched in TAM67-negative versus -positive epidermis. |
| 0.97 | filaggrin, filaggrin2, late cornified envelope precursor proteins, hair keratins and hair keratin-associated proteins. | |
| 28068897 | 0.98 | filaggrin (Flg2) genes. |
| 0.98 | filaggrin (Flg2), small proline-rich protein 2d (Sprr2d) and repetin (Rptn) belong to this class of peptides and all are significantly up-regulated in E14 (skin) and nude (skin and epidermis) tissues (Table 1). | |
| 30713093 | 0.98 | Filaggrin (FLG2) positive SCC cells (Figure 1F). |
| 0.94 | Filaggrin (FLG2) and Involucrin (IVL) expression in shPitx1 compared to shScr control cells after Ca2+ induced differentiation in culture. | |
| 23531535 | 0.98 | filaggrin, hornerin, and filaggrin 2. |
| 24999590 | 0.98 | Flg and the related filaggrin-2 (Flg2) gene was observed in hypoxic primary keratinocytes at the mRNA and protein level (Figure 2a-b). |
| 25753147 | 0.98 | filaggrin-like gene family, filaggrin, repetin, hornerin, and filaggrin 2. |
| 28248300 | 0.98 | Flg, Flg2, and the late cornified envelope genes Lce1a, b) in Pnpla1-/- epidermis (Supplementary Fig. 3a). |
| 26371476 | 0.97 | filaggrin, or its precursor profilaggrin, FLG2 is proteolytically processed during epidermal terminal differentiation and possesses similar biochemical properties. |
| 0.96 | FLG2 C-terminus just as little is known as for the filaggrin C-terminus; it was suggested that it is necessary for proper processing of the precursor profilaggrin into smaller subunits. | |
| 27021404 | 0.97 | Flg, Lor and Klk7 (Fig 1, A) but not Ivl or Flg2. |
| 0.72 | Flg, Flg2, Ivl and Lor in mast cell deficient Kit W-sh/W-sh and WT mice. | |
| 24780931 | 0.96 | Flg), filaggrin 2 (Flg2), hornerin (Hrnr), repetin (Rptn), trichohyalin (Tchh), and trichohyalin-like 1 (Tchhl1). |
| 26644517 | 0.94 | filaggrin, and filaggrin-2 were decreased in both KOs (Fig. 8 B). |
| 19387477 | 0.93 | Flg gene may indicate the presence of a specific feedback mechanism because by RT-PCR we observe no change in expression of the other tandemly arrayed filaggrin-like genes (filaggrin-2, hornerin, cornulin, repetin, trichohyalin) (data not shown). |
| 23615774 | 0.91 | filaggrin-KO mice, and likely originated from other minor sources of NMFs, such as filaggrin 2. |
| 28526300 | 0.90 | filaggrin protein is associated with loss of filaggrin mRNA (Fig. 4E) and that filaggrin 2 encoding mRNA is also reduced (Fig. 4E). |
| 25695608 | 0.88 | filaggrin-2 amount, as it has not been observed in filaggrin-null mice, filaggrin knockdown RHEs or patients with FLG nonsense mutations. |
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