Publication for Flg and Flg2

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Flg filaggrin 14246 [link]
mmu Flg2 filaggrin family member 2 229574

Pubmed ID Priority Text
25695600 0.98 Filaggrin-related proteins, including filaggrin2, trichohyalin and cornulin, are also enriched in TAM67-negative versus -positive epidermis.
0.97 filaggrin, filaggrin2, late cornified envelope precursor proteins, hair keratins and hair keratin-associated proteins.
28068897 0.98 filaggrin (Flg2) genes.
0.98 filaggrin (Flg2), small proline-rich protein 2d (Sprr2d) and repetin (Rptn) belong to this class of peptides and all are significantly up-regulated in E14 (skin) and nude (skin and epidermis) tissues (Table 1).
30713093 0.98 Filaggrin (FLG2) positive SCC cells (Figure 1F).
0.94 Filaggrin (FLG2) and Involucrin (IVL) expression in shPitx1 compared to shScr control cells after Ca2+ induced differentiation in culture.
23531535 0.98 filaggrin, hornerin, and filaggrin 2.
24999590 0.98 Flg and the related filaggrin-2 (Flg2) gene was observed in hypoxic primary keratinocytes at the mRNA and protein level (Figure 2a-b).
25753147 0.98 filaggrin-like gene family, filaggrin, repetin, hornerin, and filaggrin 2.
28248300 0.98 Flg, Flg2, and the late cornified envelope genes Lce1a, b) in Pnpla1-/- epidermis (Supplementary Fig. 3a).
26371476 0.97 filaggrin, or its precursor profilaggrin, FLG2 is proteolytically processed during epidermal terminal differentiation and possesses similar biochemical properties.
0.96 FLG2 C-terminus just as little is known as for the filaggrin C-terminus; it was suggested that it is necessary for proper processing of the precursor profilaggrin into smaller subunits.
27021404 0.97 Flg, Lor and Klk7 (Fig 1, A) but not Ivl or Flg2.
0.72 Flg, Flg2, Ivl and Lor in mast cell deficient Kit W-sh/W-sh and WT mice.
24780931 0.96 Flg), filaggrin 2 (Flg2), hornerin (Hrnr), repetin (Rptn), trichohyalin (Tchh), and trichohyalin-like 1 (Tchhl1).
26644517 0.94 filaggrin, and filaggrin-2 were decreased in both KOs (Fig. 8 B).
19387477 0.93 Flg gene may indicate the presence of a specific feedback mechanism because by RT-PCR we observe no change in expression of the other tandemly arrayed filaggrin-like genes (filaggrin-2, hornerin, cornulin, repetin, trichohyalin) (data not shown).
23615774 0.91 filaggrin-KO mice, and likely originated from other minor sources of NMFs, such as filaggrin 2.
28526300 0.90 filaggrin protein is associated with loss of filaggrin mRNA (Fig. 4E) and that filaggrin 2 encoding mRNA is also reduced (Fig. 4E).
25695608 0.88 filaggrin-2 amount, as it has not been observed in filaggrin-null mice, filaggrin knockdown RHEs or patients with FLG nonsense mutations.



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