Publication for Foxm1 and Aurkb

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Foxm1 forkhead box M1 14235 [link]
mmu Aurkb aurora kinase B 20877

Pubmed ID Priority Text
30992007 0.98 Aurora B kinase (AURKB), survivin, centromere protein A (CENPA) and CENPB, are under the transcriptional control of FOXM1.
0.98 FOXM1 pathway (downstream targets include survivin, cyclin B1, SKP2, PLK1, Aurora B kinase, CDC25B, and stathmin1 (STMN1)), coupled with CSC enrichment.
21448591 0.98 MPM2 and pHistH3 as mitotic markers are consistent with specific inhibition of Aurora kinase A by MLN8237 in vivo, as histone H3 is phosphorylated by Aurora kinase B.
21993994 0.98 forkhead box M1 (FOXM1) transcription factor and its targets responsible for cell cycle progression (PLK1, CDC25B, Aurora B, Cyclin B1) and encoding the SCF ubiquitin ligase degradation complex (SKP2, CKS1) were all predominantly upregulated in AKT/Ras preneoplastic and neoplastic lesions (Fig. 7A).
24194502 0.98 FOXM1, AURKB, and PLK1 was significantly increased in islets from high-diet responder mice, albeit to a lesser extent than in infused rats (Supplementary Fig. 1).
29426892 0.97 Aurkb, Foxm1, Incenp, and Gsg2 are important in centromere structure and dynamics.
26236688 0.96 FOXM1 pathway, all of which (or their mouse homolog) were amplified in the TCGA data set and in the MOEHIGH cell model: CHEK2, ATR, BRCA1, BRCA2, RAD51, CDC25B, BIRC5, AURKB, PLK1, and CCNB1 (Figure 5B).
30670377 0.95 Foxm1, Ccnb1, Ccnd1, and AurKB were unchanged between Foxf1fl/fl and alphaSMACreER;Foxf1-/- livers (Fig. 4D).
26350477 0.93 Aurkb, Birc5 and Nek2), and cdk inhibitors (cdkn1b and cdkn1c) were not affected between the mice, although many of these genes have been shown as FoxM1 transcriptional targets in other cell types.
29740591 0.86 Aurkb), pro-proliferation markers (Bub1, Cdk1, Foxm1, Nrg1) and decreased expression of proliferation inhibitors (Nox4, Sfrp).
25949108 0.56 AurkB, RB1, Itm2b, Ncam, Tsc22, Foxm1, nectin3-alpha gene, nectin3-beta gene, nectin3-gamma gene were not changed by the density increase (Fig. 4A).
29672594 0.52 Foxm1, Mybl2, and Uhrf1 are downregulated, and pydc4/Ifi16 (interferon gamma inducible protein 16) is upregulated in Tregs from Foxp3YFP-Cre mice; cell cycle kinases: Ccnb2, Aurkb, and Chek1 are also downregulated in Foxp3YFP-Cre mice Tregs; immune cell genes such Tnfrsf9 (CD137), Ccl2, Ccr5, and Il1r1 are downregulated, in contrast C5ar1, CD19, Il1r2, Itga2b (CD41), Ly6c1, and Tlr7 are upregulated in Foxp3YFP-Cre mice Tregs.



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