Publication for Cyp8b1 and Slco1a1
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| mmu | Cyp8b1 | cytochrome P450, family 8, subfamily b, polypeptide 1 | 13124 | [link] | ||
| mmu | Slco1a1 | solute carrier organic anion transporter family, member 1a1 | 28248 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 29175453 | 0.98 | Cyp8b1, Cyp27a1, and Cyp7b1) and transporters (Ntcp, Oatp1a1, Oatp1b2, and Mrp3). |
| 28855630 | 0.97 | Cyp8b1, Ntcp, Oatp1, Oatp4, Mrp3, Mrp4, Bsep, and Mrp2 in liver and the reduced Fgf15 and Ibabp in ileum by ANIT exposure. |
| 0.59 | Cyp8b1), basolateral uptake transporters (Ntcp, Oatp1 and Oatp4), basolateral efflux transporters (Ostbeta, Mrp3 and Mrp4), and canalicular transporters (Bsep and Mrp2). | |
| 29498526 | 0.97 | Cyp8b1, Oatp1, and Oatp2, were all down-regulated in the cholestatic groups. |
| 23470335 | 0.96 | Cyp8b1), and decreases in liver bile acid transporters (Ntcp, Bsep, Oatp1a1, Oatp1b2, and Ostbeta). |
| 30464200 | 0.95 | Cyp8b1 expression, while no changes in the expression of BA transporters (Bsep, Ntcp, Oatp1 and Oatp2) and FGF19 receptors (Fgfr4 and beta-klotho) were found (data not shown), indicating that FGF19-M52 globally reduces BA levels without a direct transcriptional impact on their secretory or transport genes. |
| 30766963 | 0.95 | cytochrome P450 family 8 subfamily B member 1 [Cyp8b1], Cyp27a1, biliary BA secretion (Abcb11), PC secretion (Abcb4), and BA import from the circulation (sodium-taurocholate cotransporting polypeptide [Ntcp], organic anion cotransporting polypeptide [Oatp1]) were all significantly lower in Pemt-/- mice than in Pemt+/+ mice (Fig. 3B). |
| 29366871 | 0.89 | Slco1a1 and Slco1b2, as well as bile-acid-synthesizing enzymes Cyp7a1 and Cyp8b1 (Figs. 2 and 3) were all observed in Cyp1a1(-/-) but not wild-type mice receiving the Western diet plus BaP. The combined treatment also increased MRP4 protein levels and decreased OATP1A1 protein levels in the liver of Cyp1a1(-/-) mice (Fig. 2). |
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