Publication for COL11A1 and MMP13

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa COL11A1 collagen type XI alpha 1 chain 1301 [link]
hsa MMP13 matrix metallopeptidase 13 4322

Pubmed ID Priority Text
21155761 0.98 COL11A1=collagen, type XI, alpha 1; HGF= hepatocyte growth factor (hepapoietin A; scatter factor); MET= met proto-oncogene (hepatocyte growth factor receptor); MMP1=matrix metallopeptidase 1 (interstitial collagenase); MMP2=matrix metallopeptidase 2 (gelatinase A); MMP3=matrix metallopeptidase 3 (stromelysin 1, progelatinase); MMP9=matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); MMP13= matrix metallopeptidase 13 (collagenase 3); LUM=lumican; PAX6= paired box 6; TGFB1= transforming growth factor, beta 1; TGFB2= transforming growth factor, beta 2.
30042390 0.98 Col11a1), ECM remodeling metallopeptidases (Mmp3, Mmp13, Mmp15, Adamts3, Adamts18), ECM glycoproteins (St8sia2, Rspo3, Lama5, Edil3, Thbs4) and cell adhesion molecules (Cldn3, Cldn7, Cldn1, Cdh2, Cdh15) (Fig. 2c).
27501229 0.97 MMP13), and deletion of 1p21.1p11.2 (COL11A1 and GSTM3), 3p14.2 (FHIT), 3p26.1 (GRM7), 3p13 (FOXP1), 9p21.3 (CDKN2A and CDKN2B), and 18q12.1q23 (SERPINB2), all of which were involved in tumor cell proliferation and angiogenesis in oral carcinogenesis.
29358879 0.96 MMP13, COL11A1, BMP7, MMP12, LAMC2, COL27A1, ITGB4, PDGFRA, ADAMTS2, IBSP, COL10A1, COL7A1, MMP11, MFAP2, MMP1, and COL1A1.
21156214 0.95 MMP-13, MMP-8, MMP-26) transmembrane molecules (selectin-E, selectin-P), ECM protease inhibitors (TIMP-3), adhesion molecules (laminin-alpha-2, thrombospondin-1, tetranectin, tenascin-C), and collagens (COL11A1, COL15A1, COL16A1, COL8A1).
26587043 0.95 COL11A1:was inhibited and that of hypertrophic phenotype genes:RUNX2 and MMP-13:was stimulated.
27609069 0.94 MMP13, MMP14, FAP, LOX and COL1A2, FAP was also differentially expressed between inflamed/fibrotic tissues and cancer tissues although this difference in expression was not as prominent as for COL11A1 (compare Fig. S9B and Fig. 4B).
22235100 0.92 MMP13), fibronectin, collagens (COL1A2, COL8A1, COL10A1, and COL11A1).
22752873 0.92 Col11a1 cause an altered cartilage collagen fibril structure leading to over-exposure of Col2a1 to DDR2, which, in turn, up-regulates the expression of matrix metalloproteinase 13 (MMP-13) and hence, degeneration of cartilage that is associated with disease.
22514560 0.91 COL11A1, COL10A1, FN1, COL12A1, MMP13, THBS2, SPARC, LRRC15, and ASPN), b) cell adhesion (GJB2), c) extracellular matrix remodelling and cell motility (PLAUR, PLAU, MMP11, and MMP14), d) calcium and metal binding and transport (GPC6, ADAMTS16, and BGN), most of which are members of the small proteoglycans family, e) genes encoding signal transducers (RGS16, ADORA3, PRR5L, and SPSB1), and f) enzymes involved in tumor growth (ENNP2 and ST6GAL2).
27857161 0.91 COL11A1, COL10A1, MMP1 and MMP13 are highly expressed in aggressive molecular subtypes (basal and HER2 tumors) in the Lebanese as their expression increases tumor migration and proliferation.
24916766 0.90 collagen type XI, alpha 1 (COL11A1), epiphycan (EPYC), and activated matrix metallopeptidase 13 (MMP13) but not the expression of sulfatase 1 (SULF1) or TNFSF4 (Figure 4C).
24950699 0.87 COL11A1, COL10A1, FN), matrix metalloproteinases (MMP9, MME, MMP13, MMP1), FAP (a marker of fibroblast activation), and growth regulator proteins.
30572540 0.67 COL11A1, MMP13, VTCN1, COL10A1, and SLC18A3 were the most significantly upregulated DEGs in the TCPTC tissues, while CA4, EDN3, TPO, PKHD1L1 and FOXJ1 were the most significantly downregulated DEGs in the TCPTC tissues compared with the cPTC tissues.
26351771 0.58 COL11A1; COL14A1; COL16A1; contactin 1; connective tissue growth factor (CTGF); catenin, alpha 1; catenin Delta 2; integrin beta 2 (ITGB2); kallmann syndrome 1 sequence (KAL1); laminin alpha 3 (LAMA3); matrix metallopeptidase 2 (MMP2); MMP3; MMP7; MMP12; MMP13; selectin E; secreted protein acidic, cysteine-rich (SPARC); transforming growth factor, beta-induced; Thrombospondin 3 (THBS3); and Versican (VCAN).
28881680 0.55 MMP13, COL11A1, COL1A1, ITGA11, VACN, THBS2 and TIMP1, which were significantly enriched in cell adhesion molecules and focal adhesion pathways and enriched in cell adhesion, response to hypoxia, signal transduction and positive regulation of cell proliferation of GO biological process.



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