Publication for COL5A2 and FN1
| Species | Symbol | Function* | Entrez Gene ID* | Other ID | Gene coexpression |
CoexViewer |
|---|---|---|---|---|---|---|
| hsa | COL5A2 | collagen type V alpha 2 chain | 1290 | [link] | ||
| hsa | FN1 | fibronectin 1 | 2335 |
| Pubmed ID | Priority | Text |
|---|---|---|
| 30948703 | 0.97 | COL5A2, COL11A1, COL18A1, FN1, and SPARC was related to poor OS in patients with GC. |
| 0.93 | COL5A2, FN1, THBS1, COL5A1, SPARC, COL18A1, and COL11A1. | |
| 0.55 | COL5A2, FN1, THBS1, COL5A1, SPARC, COL18A1, and COL11A1. | |
| 0.52 | COL5A2, FN1, THBS1, COL5A1, SPARC, COL18A1, and COL11A1 - were confirmed as hub genes (Table 2, Figure 5A). | |
| 29237464 | 0.97 | fibronectin (FC = +9.2), Collagen type V, alpha2 (ColVA2) (FC = +3.1), Integrin A5 (ITGA5) (FC = + 4.9) or Pleckstrin 2 (PLEK2) (FC = +4.8) along with a downregulation of Wnt11 (FC = -19.1) (Fig. 2a and Additional file 1: Table S1). |
| 0.96 | fibronectin, ColVA2, ITGA5 and PLEK2 was notably confirmed, with a dramatic and significant upregulation of expression in the TGF-beta + poly(I:C) condition (Fig. 2b). | |
| 31706267 | 0.96 | COL5A2) + 0.2361*log2(FN1)-0.0729*log2(COL1A2)-0.0560*log2(FAP) + 0.1020*log2(POSTN), log2(gene count). |
| 0.96 | COL5A2, FN1, COL1A2, FAP and POSTN were identified by lasso regression analysis from DEGs and could diagnose the PC. | |
| 0.95 | COL5A2, FN1, COL1A2, FAP and POSTN) as a specific predictive signature for the diagnosis of PC. | |
| 29719832 | 0.95 | FN1 and type Valpha2 collagen (COL5A2)] (Figure 1I), indicative of enhanced microenvironment-adaptive activity in the malignant cells. |
| 30816427 | 0.95 | FN1, MMP9, COL6A1, COL5A2, COL6A2, ITGA5, FBN1, CTGF, ITGA4, PDGFRB, LUM, PPIB, MMP14, ITGA11 and COPB1 (Table II). |
| 17411443 | 0.94 | COL5A2, IGFBP3, FN1, ANXA2, BGN and PTGDS) and all 4 genes detected from the z-statistic as effect size (PTTG1, COL5A2, IGFBP3 and PTGDS) are associated with angiogenesis. |
| 22228636 | 0.93 | FN1, a member of the integrin signaling pathway, and several other members or close interaction partners of this pathway were upregulated in MI as compared to non-MI tumors in most datasets we investigated; these genes include ACTN1, COL1A2, COL3A1, COL5A2, COL6A3, COL11A1, COL16A1, FBN1, FLNA, LUM, TGFBI, and TNC. |
| 20617897 | 0.92 | FN1 in the fetus increased the risk for SGA; 2) haplotypes in COL1A1 and MMP9 in the mother and FN1 in the fetus were associated with SGA; 3) multilocus analysis with MDR revealed a significant interaction between PLAU and COL5A2 in mothers; 4) pathway analysis (Supplemental Table 2) suggested that maternal and fetal genes involved in extracellular matrix function predispose to SGA; 5) importantly, TIMP2 and FN1 were found to participate in both maternal and fetal networks along with other molecules associated with SGA. |
| 31488082 | 0.92 | FN1 and CTGF, and genes involved in extracellular matrix synthesis and adhesion: COL1A1, COL5A1, COL5A2, ICAM1, and HAS2 (Table 2). |
| 30237810 | 0.89 | COL5A2, and COL11A1), integrin (ITGA6), tenascin (TNXB) and fibronectin (FN1). |
| 30633213 | 0.88 | fibronectin 1 (FN1), carboxyl ester lipase (CEL), integrin subunit alpha 2 (ITGA2), collagen type V alpha 2 chain (COL5A2), matrix metallopeptidase 1 (MMP1), and chymotrypsin-like elastase family member 3B (CELA3B). |
| 0.77 | FN1, CEL, ITGA2, COL5A2, MMP1, and CELA3B were the top 10 hub genes, which may be essential to the molecular mechanisms underlying the development of PDAC and may therefore serve as potential therapeutic targets. | |
| 27907202 | 0.84 | COL5A2, FN1 and DCN were higher than in PB. |
| 31110246 | 0.84 | COL5A2, COL6A1, COL6A2, COL6A3, COL8A1, and COL12A1), fibronectin (FN1), the matrix metalloproteinases 1, 2, and 14 (MMP1, MMP2, and MMP14), and tissue inhibitor of metalloproteinases 1, 2, and 3 (TIMP1, TIMP2, and TIMP3) were seen in all fibroblasts (Fig. 7c). |
| 30029183 | 0.78 | FN1, COL1A1, COL1A2, COL3A1, COL5A2, TWIST1, SNAI2, and ZEB1. |
| 22208948 | 0.64 | COL5A2, FAP, POSTN, COL1A2, COL3A1, FBN1, TNFAIP6, MMP2, GREM1, BGN, CDH11, SPOCK1, DCN, COPZ2, THY1, PCOLCE, PRRX1) plus the obvious EMT markers SNAI2, FN1, ACTA2. |
| 0.52 | COL5A2, COL5A1, VCAN, COL1A1, COL3A1, FN1,SULF1, FBN1, ASPN, SPARC, CTSK, MMP2, BGN, LUM, LOXL2, COL6A3, TIMP3, CDH11, SERPINF1, EDNRA, ACTA2, PDGFRB, SNAI2, LGALS1, GLT8D2, NID2, PRRX1) belong to the set of 64 genes in Table 1 (P = 10-27), as well as VIM (vimentin). |
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