Publication for COL5A2 and COL6A2

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa COL5A2 collagen type V alpha 2 chain 1290 [link]
hsa COL6A2 collagen type VI alpha 2 chain 1292

Pubmed ID Priority Text
31123405 0.97 COL6A2, COL6A1, COL5A2, COL1A2, and COL1A1 mRNA levels were increased in the MIBC compared to NMIBC in the Sanchez-Carbayo bladder database.
0.97 COL5A2, COL6A1, COL6A2, and COL6A3) involved in the ECM-receptor interaction signaling pathway in BCa progression.
0.94 COL5A2, COL6A1, COL6A2, and COL6A3, favoring NMIBC progression to MIBC.
0.90 COL6A2, COL6A1, COL5A2, COL1A2 and COL1A1 in the MIBC and NMIBC samples.
0.89 COL5A2, COL6A1, COL6A2, and COL6A3) were up-regulated and gathered in the ECM-receptor interaction signal pathway identified by KEGG pathway analysis and GSEA.
0.88 COL5A2, COL6A1, COL6A2, COL6A3, MMP9, THY1, TAGLN, VIM, CTGF, PDGFRB, ACTA2, SPP1, and TPM2 interacted closely with each other (Figure 1B).
0.88 COL6A2, COL6A1, COL5A2, COL1A2, and COL1A1 genes in MIBC tissues compared to NMIBC tissues.
0.62 COL6A2, COL6A1, COL5A2, COL1A2, and COL1A1 mRNA levels were up-regulated in MIBC compared to NMIBC based on the Dyrskjot bladder database from Oncomine.
28586059 0.97 COL5A2, COL6A1, COL6A2, COL6A3, COL11A1, COL12A1 and integrin alpha4 (ITGA4) may interact with each other in the dM2 module.
0.93 COL6A2, COL6A1, ITGA4, COL1A1, COL11A1 and COL5A2) and neuroactive ligand-receptor interaction (dM3; P=9.49x10-4; Table IVB).
0.52 COL5A2, COL6A1, COL6A2, COL6A3, COL11A1, COL12A1 and ITGA4 may interact with each other.
28349952 0.96 COL5A2, VIM, TGFBI, IGFBP2, IGFBP4, COL6A2, MMP2, HTRA1), and immune response (HTRA1, NID, TAC1, C1R, PTX3).
31137733 0.96 COL6A2, COL1A1, COL1A2, COL4A5, COL7A1, BGN, COL5A1, COL5A2, COL16A1, BMP1, and SERPINH1 were involved in module 1.
22384228 0.93 Col-5a2, Col-5a3, Col-6a2, Col-8a1, Col-9a1, Col-9a2, Col-9a3, Col-11a2, Col-16a1, Col-18a1, Col-27a1, Ctnnbeta1, Ddr2, Fgfr2, Fgfr3, Fgfbp3, Fap, Fgf13, Gbx2, Mst1, Igsf10, Sdc2, Sfrp2, Tgfbeta1, Wisp1, and Wisp3.
30410353 0.93 COL6A2, COL6A3, COL5A2, and COL11A1 are members of the collagen family, and these five genes are enriched in the pathway of "ECM-receptor interaction", which leads to a direct or indirect control of cellular activities such as adhesion, migration, differentiation, proliferation, and apoptosis.
31110246 0.91 COL5A2, COL6A1, COL6A2, COL6A3, COL8A1, and COL12A1), fibronectin (FN1), the matrix metalloproteinases 1, 2, and 14 (MMP1, MMP2, and MMP14), and tissue inhibitor of metalloproteinases 1, 2, and 3 (TIMP1, TIMP2, and TIMP3) were seen in all fibroblasts (Fig. 7c).
31258820 0.91 COL5A2 (fold change = 0.24, p = 0.003), COL6A1 (fold change = 0.40, p = 0.001), COL6A2 (fold change = 0.44, p = 0.0005), COL6A6 (fold change = 0.40, p = 0.002), COL8A1 (fold change = 0.33, p = 0.0009), FGFR4 (fold change = 0.39, p = 0.00001), ITPR1 (fold change = 0.59, p = 0.00006), LAMA2 (fold change = 0.58, p = 0.003), LYN (fold change = 1.54, p = 0.03), PRKCA (fold change = 0.57, p = 0.004), and PTPN11 (fold change = 0.37, p = 0.001).
21635755 0.75 COL6A2, COL1A1, COL1A2, and COL5A2, were prominent in the macrodissected samples and presumably contributed by the stromal cells.
23385231 0.53 COL5A2, COL6A1, COL6A2, COL7A1, COL8A2, and COL18A1 (Table S2).
32092127 0.51 COL5A2, COL6A1, COL6A2, COL6A3, COL14A1, COL27A1, MFAP2, MFAP4 and MFAP5), cell adhesion (LAMA1, LAMA2, LAMB1, LAMB2, LAMB3, LAMC1, TGFBI, TGFBP7, NPNT, FREM2, SPON1, CD151, FBLN1, GLG1, LGALS3BP, MYOC, ADAMTS6, THBS2, EFEMP1, FRAS1 and ITGA10) and extracellular matrix interaction (ADAMTSL2, COL4A1, COL17A1, SOD3, SPARC, DAG1, LAMA3, LAMC3, CASK, SSC5D, NID1, PRELP, VCAN, COMP, SMAD3 and ITGA11) were dominantly upregulated in cattleyak with respect to yak (S6 Table).



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