Publication for Cfl1 and Wdr1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
mmu Cfl1 cofilin 1, non-muscle 12631 [link]
mmu Wdr1 WD repeat domain 1 22388

Pubmed ID Priority Text
29675452 0.98 cofilin-1, cofilin-2) severs and disassembles existing filaments, an activity that is significantly enhanced by the cofactor actin-interacting protein 1.
0.98 cofilin-1 in regulating the remodeling and permeability of epithelial junctions because loss of either cofilin-1, ADF, or actin-interacting protein 1 was associated with increased epithelial permeability, delayed AJC assembly, and increased susceptibility to dextran sodium sulfate-induced colitis.
27627652 0.98 Wdr1-enhanced cofilin1-induced actin turnover.
25915128 0.97 Wdr1 might affect PCP, we were intrigued by a recent report that depletion of Cfl1 in looptail (Vangl2) mutant mice accentuates PCP defects within the node and midline cells of early post-gastrulation (E9.5) mouse embryos.
0.97 Wdr1, cofilins and actin dynamics is interesting in light of the recent surfacing of cofilin (Cfl1) in a genetic screen for PCP mutants in the early mouse embryo.
0.64 Cfl1 and/or Dstn mimics the Wdr1-KD phenotype.



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