Publication for EIF1 and EIF1B

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	EIF1	eukaryotic translation initiation factor 1	10209			[link]
hsa	EIF1B	eukaryotic translation initiation factor 1B	10289

Pubmed ID	Priority	Text
28541577	0.98	eIF1B and eIF1 double knockdown on cell proliferation (Supplementary Figure S10, Figure 9E).
	0.98	eIF1 gene in HAP1 cells was not originally anticipated and the nearly 3-fold upregulation of eIF1B in eIF1KO cells suggested a possible functional overlap between these paralog genes.
	0.97	eIF1B for the growth of human cells during eIF1 deprivation.
	0.95	eIF1 and its paralog gene eIF1B, we complemented the studies performed upon eIF1 knockdown with label-free shotgun proteomics data from eIF1 knockout (eIF1KO) and eIF1B knockout (eIF1BKO) HAP1 cell lines (Figure 1A).
	0.95	eIF1 also recognizes the highly similar in sequence eIF1B.
	0.95	eIF1 and eIF1B in WT or eIF1B KO HAP-1 cells (Supplementary Figure S9).
	0.95	eIF1 expression, the overall mildly perturbed to unperturbed proteome expression profile of eIF1BKO cells observed, and the apparent lack of combined eIF1 and eIF1B knockdown on cell viability prohibit from drawing any conclusion regarding eIF1B activity.
	0.92	eIF1 deprivation impacted a widespread regulation of the eIF network, including eIF5, eIF1B and eIF4B.
	0.85	eIF1 in HCT116 cells and shotgun proteomics data of eIF1 and eIF1B knockout HAP1 cell lines.
	0.84	eIF1 and/or knockdown of its paralog gene eIF1B.
	0.68	eIF1 knockdown and knockout conditions, we observed a significant downregulation of eIF5, while eIF4B and eIF1B were upregulated.
	0.68	eIF1B becomes indispensable for cell growth upon eIF1 deprivation, we performed a double knockdown of eIF1 and eIF1B in both WT and eIF1BKO HAP1 cells.
17353931	0.97	GC20 and EIF3S10 identified many of the EIF3 components (EIF1 (GC20 homolog) has previously been shown to interact with EIF3).
18381591	0.72	EIF1, EIF1B, EIF2A and EIF2C3 (Argonaute3), whereas those transcripts that encode negative regulators of the translation factors, such as eukaryotic translation initiation factor 2- alpha kinase (EIF2AK2) an interferon induced kinase that phosphorylates EIF2A and eukaryotic translation initiation factor 4E binding protein 2 (EIF4EBP2) a protein that binds to EIFE to inhibit protein translation, are repressed by proteasome inhibition (Figure 4D, Table 4-2).