Publication for CDH5 and GPR4

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa CDH5 cadherin 5 1003 [link]
hsa GPR4 G protein-coupled receptor 4 2828

Pubmed ID Priority Text
30874584 0.98 CDH5 (VE-cadherin), OX2G (OX-2 membrane glycoprotein; CD200), GPR4 (G protein-coupled receptor 4), CACNG7 (calcium voltage-gated channel auxiliary subunit gamma 7) and F11R (F11 receptor; junctional adhesion molecule A; JAM-A; CD321) were selected for validation.
0.98 G protein-coupled receptor 4 (GPR4) and cadherin 5 (CDH5), were similarly upregulated in CPC relative to MSC and HDF (Fig. 1d; Supplementary Fig. S2).
0.98 GPR4 (b), CDH5 (c), F11R (d), CACNG7 (e) in CPCS (p2) (blue bars) compared with total human heart tissue (black) bars and cardiac fibroblasts (HCF6300, HFCc; grey bars); values relative to GAPDH expression.
0.98 GPR4, F11R and CDH5 markers was performed in three CPC isolates (CPC1-3), compared with the cardiac fibroblast HCF6300.
0.98 CDH5 (VE-cadherin), GPR4, CACNG7, F11R (JAM-A; CD321) and CD200 (OX2G) were selected for validation.
0.98 GPR4, CDH5 and F11R fulfill all the criteria to be highly preferentially expressed in CPC compared with the other cell lineages analyzed, and in particular with cardiac fibroblasts.
0.97 CDH5, FR11, GPR4 gene expression from independent CPC donors (CPC1-3; blue bars), two HDF (HDF and F3; red bars), and two independent MSC (MSC19, MSC45; green bars).
0.97 GPR4, CACNG7, F11R and CDH5 defines a heterogeneous population of human CPC, isolated based on c-KIT+ expression and expanded in the conditions equivalent to that used in the CARE-MI clinical trial.
0.96 CDH5 showed (at p2) the greatest expression (52.8%) in CPCS, followed by GPR4 (38.9%), CACNG7 (26.8%) and F11R (20.1%).
0.95 GPR4 and CDH5 markers was performed in three CPC isolates (CPC1-3), with MSC (MSC19) and HDF as controls.
0.81 CDH5, GPR4, CACNG7, CD200 and F11R were validated in human and porcine samples.
0.69 GPR4, F11R, CACNG7 and CDH5 are human CPC surface-expressed proteins that can be used in combination with c-KIT, for a variety of downstream applications.
0.58 GPR4 and CDH5 in CPC (blue bars) compared with total human heart tissue (grey bars); values relative to GAPDH expression.



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