KEGG 00100 Steroid biosynthesis
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) cel(Nematoda) mcc(Monkey) cfa(Dog) sce(Budding yeast) spo(Fission yeast) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00100 Steroid biosynthesis 12
hsa00900 Terpenoid backbone biosynthesis 6
hsa00280 Valine, leucine and isoleucine degradation 3
hsa00650 Butanoate metabolism 3
hsa01212 Fatty acid metabolism 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu00100 Steroid biosynthesis 13
mmu00900 Terpenoid backbone biosynthesis 7
mmu04979 Cholesterol metabolism 3
mmu01212 Fatty acid metabolism 3
mmu04976 Bile secretion 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno00100 Steroid biosynthesis 12
rno00900 Terpenoid backbone biosynthesis 6
rno01212 Fatty acid metabolism 3
rno04152 AMPK signaling pathway 2
rno04976 Bile secretion 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga00100 Steroid biosynthesis 12
gga00900 Terpenoid backbone biosynthesis 6
gga01240 Biosynthesis of cofactors 2
gga00630 Glyoxylate and dicarboxylate metabolism 2
gga01200 Carbon metabolism 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre00100 Steroid biosynthesis 17
dre00900 Terpenoid backbone biosynthesis 8
dre00280 Valine, leucine and isoleucine degradation 3
dre00650 Butanoate metabolism 3
dre01212 Fatty acid metabolism 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel04142 Lysosome 2
cel00100 Steroid biosynthesis 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc00100 Steroid biosynthesis 13
mcc00900 Terpenoid backbone biosynthesis 4
mcc04142 Lysosome 2
mcc04979 Cholesterol metabolism 2
mcc03320 PPAR signaling pathway 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa00100 Steroid biosynthesis 13
cfa00900 Terpenoid backbone biosynthesis 5
cfa03320 PPAR signaling pathway 3
cfa01212 Fatty acid metabolism 2
cfa04146 Peroxisome 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sce00100 Steroid biosynthesis 14
sce00900 Terpenoid backbone biosynthesis 3
sce00909 Sesquiterpenoid and triterpenoid biosynthesis 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
spo00100 Steroid biosynthesis 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca00100 Steroid biosynthesis 14
fca00900 Terpenoid backbone biosynthesis 3
fca04928 Parathyroid hormone synthesis, secretion and action 2
fca01040 Biosynthesis of unsaturated fatty acids 2
fca01212 Fatty acid metabolism 2
Gene list in the network
Symbol Function*
ACAT2 acetyl-CoA acetyltransferase 2
CYP51A1 cytochrome P450 family 51 subfamily A member 1
DHCR7 7-dehydrocholesterol reductase
DHCR24 24-dehydrocholesterol reductase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
LSS lanosterol synthase
MVD mevalonate diphosphate decarboxylase
MVK mevalonate kinase
MSMO1 methylsterol monooxygenase 1
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase
SQLE squalene epoxidase
TM7SF2 transmembrane 7 superfamily member 2
LIPG lipase G, endothelial type
EBP EBP cholestenol delta-isomerase
ERG28 ergosterol biosynthesis 28 homolog
NSDHL NAD(P) dependent steroid dehydrogenase-like
RDH11 retinol dehydrogenase 11
HSD17B12 hydroxysteroid 17-beta dehydrogenase 12
HSD17B7 hydroxysteroid 17-beta dehydrogenase 7
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
AACS acetoacetyl-CoA synthetase
HSD17B7P2 hydroxysteroid 17-beta dehydrogenase 7 pseudogene 2
TMEM41B transmembrane protein 41B
Symbol Function*
Cyp51 cytochrome P450, family 51
Dhcr7 7-dehydrocholesterol reductase
Ebp phenylalkylamine Ca2+ antagonist (emopamil) binding protein
Fdft1 farnesyl diphosphate farnesyl transferase 1
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7
Ldlr low density lipoprotein receptor
Lipa lysosomal acid lipase A
Lss lanosterol synthase
Rdh11 retinol dehydrogenase 11
Nsdhl NAD(P) dependent steroid dehydrogenase-like
Sqle squalene epoxidase
Srebf2 sterol regulatory element binding factor 2
Echdc1 enoyl Coenzyme A hydratase domain containing 1
Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12
Erg28 ergosterol biosynthesis 28
Msmo1 methylsterol monoxygenase 1
Ccdc25 coiled-coil domain containing 25
Pmvk phosphomevalonate kinase
Pcyt2 phosphate cytidylyltransferase 2, ethanolamine
Tm7sf2 transmembrane 7 superfamily member 2
Dhcr24 24-dehydrocholesterol reductase
Mfsd13a major facilitator superfamily domain containing 13a
Fads1 fatty acid desaturase 1
Mmab methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
Pcsk9 proprotein convertase subtilisin/kexin type 9
Fdps farnesyl diphosphate synthetase
Acat2 acetyl-Coenzyme A acetyltransferase 2
Stard4 StAR-related lipid transfer (START) domain containing 4
Mvd mevalonate (diphospho) decarboxylase
Utp14b UTP14B small subunit processome component
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Zdhhc9 zinc finger, DHHC domain containing 9
Tmem41b transmembrane protein 41B
Sc5d sterol-C5-desaturase
Idi1 isopentenyl-diphosphate delta isomerase
LOC118568156 uncharacterized LOC118568156
Symbol Function*
Cyp51 cytochrome P450, family 51
Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
Sqle squalene epoxidase
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7
Fdft1 farnesyl diphosphate farnesyl transferase 1
Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1
Dhcr7 7-dehydrocholesterol reductase
Insig1 insulin induced gene 1
Lss lanosterol synthase
Mvd mevalonate diphosphate decarboxylase
Fdps farnesyl diphosphate synthase
Scd2 stearoyl-Coenzyme A desaturase 2
Fads1 fatty acid desaturase 1
Idi1 isopentenyl-diphosphate delta isomerase 1
Pcyt2 phosphate cytidylyltransferase 2, ethanolamine
Sc5d sterol-C5-desaturase
Ebp EBP, cholestenol delta-isomerase
Msmo1 methylsterol monooxygenase 1
Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2
Stard4 StAR-related lipid transfer domain containing 4
Tm7sf2 transmembrane 7 superfamily member 2
Pcsk9 proprotein convertase subtilisin/kexin type 9
Dhcr24 24-dehydrocholesterol reductase
Erg28 ergosterol biosynthesis 28 homolog
Srebf2 sterol regulatory element binding transcription factor 2
Ldlr low density lipoprotein receptor
Tmem97 transmembrane protein 97
Acat2 acetyl-CoA acetyltransferase 2
Nsdhl NAD(P) dependent steroid dehydrogenase-like
Acss2 acyl-CoA synthetase short-chain family member 2
Mmab metabolism of cobalamin associated B
Symbol Function*
SREBF1 sterol regulatory element binding transcription factor 1
LDLR low density lipoprotein receptor
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
SREBF2 sterol regulatory element binding transcription factor 2
ACLY ATP citrate lyase
PANK3 pantothenate kinase 3
TRAF7 TNF receptor associated factor 7
PGP phosphoglycolate phosphatase
TMEM132B transmembrane protein 132B
SCPEP1 serine carboxypeptidase 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MFSD2A major facilitator superfamily domain containing 2A
SQLE squalene epoxidase
IDI2 isopentenyl-diphosphate delta isomerase 2
PEX1 peroxisomal biogenesis factor 1
ACAT2 acetyl-CoA acetyltransferase 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
CETN1 centrin 1
MSMO1 methylsterol monooxygenase 1
DHCR7 7-dehydrocholesterol reductase
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
ERG28 ergosterol biosynthesis 28
LIPA lipase A, lysosomal acid type
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
HSD17B7 hydroxysteroid 17-beta dehydrogenase 7
SOAT1 sterol O-acyltransferase 1
DHCR24 24-dehydrocholesterol reductase
FDPS farnesyl diphosphate synthase
MVD mevalonate diphosphate decarboxylase
MVK mevalonate kinase
LOC100857622 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase-like
SC5D sterol-C5-desaturase
LOC107054034 uncharacterized LOC107054034
Symbol Function*
acat2 acetyl-CoA acetyltransferase 2
scarb2a scavenger receptor class B, member 2a
cel.1 carboxyl ester lipase, tandem duplicate 1
insig1 insulin induced gene 1
dhcr7 7-dehydrocholesterol reductase
elovl5 ELOVL fatty acid elongase 5
ldlrb low density lipoprotein receptor b
aacs acetoacetyl-CoA synthetase
hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
msmo1 methylsterol monooxygenase 1
cyp51 cytochrome P450, family 51
rdh12 retinol dehydrogenase 12
ebp EBP cholestenol delta-isomerase
sc5d sterol-C5-desaturase
mvk mevalonate kinase
mvda mevalonate (diphospho) decarboxylase a
tm7sf2 transmembrane 7 superfamily member 2
dhcr24 24-dehydrocholesterol reductase
nsdhl NAD(P) dependent steroid dehydrogenase-like
stard4 StAR-related lipid transfer (START) domain containing 4
fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
idi1 isopentenyl-diphosphate delta isomerase 1
hmgcra 3-hydroxy-3-methylglutaryl-CoA reductase a
cyp2r1 cytochrome P450, family 2, subfamily R, polypeptide 1
soat1 sterol O-acyltransferase 1
cel.2 carboxyl ester lipase, tandem duplicate 2
erg28 ergosterol biosynthesis 28 homolog
tmem97 transmembrane protein 97
fdft1 farnesyl-diphosphate farnesyltransferase 1
elovl2 ELOVL fatty acid elongase 2
cyb5r2 cytochrome b5 reductase 2
ebpl EBP like
hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7
cyp27b1 cytochrome P450, family 27, subfamily B, polypeptide 1
lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
sqlea squalene epoxidase a
pmvk phosphomevalonate kinase
srebf2 sterol regulatory element binding transcription factor 2
pcsk9 proprotein convertase subtilisin/kexin type 9
Symbol Function*
gba-4 Putative glucosylceramidase 4
lipl-5 Lipase lipl-5
Y7A5A.1 Delta(24)-sterol reductase
Symbol Function*
NSDHL NAD(P) dependent steroid dehydrogenase-like
LIPA lipase A, lysosomal acid type
FDFT1 farnesyl-diphosphate farnesyltransferase 1
MVD mevalonate diphosphate decarboxylase
LAMP1 lysosomal associated membrane protein 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
ERG28 ergosterol biosynthesis 28 homolog
CYP51A1 cytochrome P450 family 51 subfamily A member 1
MSMO1 methylsterol monooxygenase 1
STARD4 StAR related lipid transfer domain containing 4
SQLE squalene epoxidase
SC5D sterol-C5-desaturase
LSS lanosterol synthase
IDI1 isopentenyl-diphosphate delta isomerase 1
SCD stearoyl-CoA desaturase
SREBF2 sterol regulatory element binding transcription factor 2
EBP EBP cholestenol delta-isomerase
SOAT1 sterol O-acyltransferase 1
DHCR24 24-dehydrocholesterol reductase
FDPS farnesyl diphosphate synthase
INSIG1 insulin induced gene 1
LOC720399 3-keto-steroid reductase
FADS1 fatty acid desaturase 1
DHCR7 7-dehydrocholesterol reductase
Symbol Function*
CYP51A1 cytochrome P450 family 51 subfamily A member 1
MSMO1 methylsterol monooxygenase 1
TM7SF2 transmembrane 7 superfamily member 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
PEBP1 phosphatidylethanolamine binding protein 1
ACSL3 acyl-CoA synthetase long chain family member 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
FDPS farnesyl diphosphate synthase
NSDHL NAD(P) dependent steroid dehydrogenase-like
DHCR7 7-dehydrocholesterol reductase
FADS2 fatty acid desaturase 2
MVK mevalonate kinase
DHCR24 24-dehydrocholesterol reductase
LSS lanosterol synthase
SQLE squalene epoxidase
HSD17B7 hydroxysteroid 17-beta dehydrogenase 7
EBP EBP cholestenol delta-isomerase
SC5D sterol-C5-desaturase
TMEM97 transmembrane protein 97
ERG28 ergosterol biosynthesis 28 homolog
IDI1 isopentenyl-diphosphate delta isomerase 1
LOC102154725 methylsterol monooxygenase 1-like
MIR8819 microRNA mir-8819
LOC119871470 uncharacterized LOC119871470
Symbol Function*
YEH1 sterol esterase
ERG3 C-5 sterol desaturase
ERG27 3-keto-steroid reductase
ERG4 delta(24(24(1)))-sterol reductase
ERG26 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)
SCM4 Scm4p
ERG25 methylsterol monooxygenase
ERG1 squalene monooxygenase
HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
ERG6 sterol 24-C-methyltransferase
ERG5 C-22 sterol desaturase
ERG29 Erg29p
ERG2 C-8 sterol isomerase ERG2
ERG8 phosphomevalonate kinase
ERG24 delta(14)-sterol reductase
NSG2 Nsg2p
CYB5 Cyb5p
ARE2 sterol acyltransferase
MVD1 diphosphomevalonate decarboxylase MVD1
ERG11 sterol 14-demethylase
MSC7 meiotic recombination directing protein
NCP1 NADPH--hemoprotein reductase
ERG7 lanosterol synthase ERG7
ERG9 bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase
ERG28 Erg28p
Symbol Function*
are2 putative acyl-coA-sterol acyltransferase Are2
SPBC13G1.02 putative mannose-1-phosphate guanyltransferase
erg27 putative 3-keto sterol reductase
SPBC3F6.02c putative 3 beta-hydroxysteroid dehydrogenase/delta 5-to-4-isomerase
erg1 putative squalene monooxygenase Erg1
SPAC5D6.04 putative auxin family transmembrane transporter
erg31 C-5 sterol desaturase Erg31
erg11 putative sterol 14-demethylase
erg25 putative C-4 methylsterol oxidase
erg32 C-5 sterol desaturase Erg32
SPNCRNA.155
Symbol Function*
ACLY ATP citrate lyase
CYP27B1 cytochrome P450 family 27 subfamily B member 1
LSS lanosterol synthase
ELOVL6 ELOVL fatty acid elongase 6
HSD17B7 hydroxysteroid 17-beta dehydrogenase 7
CYP51A1 cytochrome P450 family 51 subfamily A member 1
TM7SF2 transmembrane 7 superfamily member 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
STARD4 StAR related lipid transfer domain containing 4
FDPS farnesyl diphosphate synthase
SQLE squalene epoxidase
INSIG1 insulin induced gene 1
DHCR7 7-dehydrocholesterol reductase
SCD stearoyl-CoA desaturase
MVD mevalonate diphosphate decarboxylase
EBP EBP cholestenol delta-isomerase
CYP24A1 cytochrome P450 family 24 subfamily A member 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
MSMO1 methylsterol monooxygenase 1
ERG28 ergosterol biosynthesis 28 homolog
DHCR24 24-dehydrocholesterol reductase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
SC5D sterol-C5-desaturase


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