[][] hsa FDFT1 Gene 
functional annotation
Function   farnesyl-diphosphate farnesyltransferase 1
GO BP
GO:0045338 [list] [network] farnesyl diphosphate metabolic process  (1 genes)  IBA  
GO:0006696 [list] [network] ergosterol biosynthetic process  (2 genes)  IEA  
GO:0008299 [list] [network] isoprenoid biosynthetic process  (11 genes)  IEA  
GO:0006694 [list] [network] steroid biosynthetic process  (24 genes)  TAS  
GO:0045540 [list] [network] regulation of cholesterol biosynthetic process  (34 genes)  TAS  
GO:0006695 [list] [network] cholesterol biosynthetic process  (40 genes)  IBA TAS  
GO:0019216 [list] [network] regulation of lipid metabolic process  (86 genes)  TAS  
GO:0055114 [list] [network] oxidation-reduction process  (533 genes)  IEA  
GO CC
GO:0005789 [list] [network] endoplasmic reticulum membrane  (882 genes)  IBA TAS  
GO:0005783 [list] [network] endoplasmic reticulum  (889 genes)  IDA  
GO:0016021 [list] [network] integral component of membrane  (3623 genes)  IEA  
GO MF
GO:0004310 [list] [network] farnesyl-diphosphate farnesyltransferase activity  (1 genes)  IBA TAS  
GO:0051996 [list] [network] squalene synthase activity  (1 genes)  IBA  
GO:0016491 [list] [network] oxidoreductase activity  (90 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9334 genes)  IPI  
KEGG hsa00100 Steroid biosynthesis
Orthologous [Ortholog page] Fdft1 (mmu)Fdft1 (rno)FDFT1 (gga)FDFT1 (cfa)fdft1 (dre)FDFT1 (mcc)ERG9 (sce)erg9 (spo)
Subcellular
localization
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 1,  E.R. 1  (predict for NP_001274671.1)
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 1,  E.R. 1  (predict for NP_001274672.1)
extr 6,  mito 1,  pero 1,  mito_pero 1  (predict for NP_001274673.1)
extr 6,  mito 1,  pero 1,  mito_pero 1  (predict for NP_001274674.1)
extr 6,  mito 1,  pero 1,  mito_pero 1  (predict for NP_001274676.1)
extr 6,  mito 1,  pero 1,  mito_pero 1  (predict for NP_001274677.1)
extr 6,  mito 1,  pero 1,  mito_pero 1  (predict for NP_001274678.1)
mito 4,  cyto_nucl 3,  nucl 2,  cyto 2,  E.R._mito 2,  cyto_pero 2  (predict for NP_001274679.1)
cysk 8,  cyto 1  (predict for NP_001274680.1)
cyto_nucl 5,  nucl 5,  cyto 4  (predict for NP_001274685.1)
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 1,  E.R. 1  (predict for NP_004453.3)
extr 6,  mito 1,  pero 1,  mito_pero 1  (predict for XP_016868706.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00100 Steroid biosynthesis 8
hsa00900 Terpenoid backbone biosynthesis 5
hsa00280 Valine, leucine and isoleucine degradation 3
hsa00650 Butanoate metabolism 3
hsa00072 Synthesis and degradation of ketone bodies 2
Genes directly connected with FDFT1 on the network
MR* Locus Fuction* Coexpression
detail
Entrez Gene ID*
35.6 MSMO1 methylsterol monooxygenase 1 [detail] 6307
56.6 FDPS farnesyl diphosphate synthase [detail] 2224
77.5 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [detail] 3157
89.8 ERG28 ergosterol biosynthesis 28 homolog [detail] 11161
132.8 SREBF2 sterol regulatory element binding transcription factor 2 [detail] 6721
149.3 HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 [detail] 51478
159.0 DHCR24 24-dehydrocholesterol reductase [detail] 1718
272.4 RUSC1-AS1 RUSC1 antisense RNA 1 [detail] 284618
Coexpressed
gene list
[Coexpressed gene list for FDFT1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 2222    
Refseq ID (protein) NP_001274671.1 
NP_001274672.1 
NP_001274673.1 
NP_001274674.1 
NP_001274676.1 
NP_001274677.1 
NP_001274678.1 
NP_001274679.1 
NP_001274680.1 
NP_001274685.1 
NP_004453.3 
XP_016868706.1 


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