functional annotation |
Function |
WW domain containing E3 ubiquitin protein ligase 2 |
|
GO BP |
GO:0006858 [list] [network] extracellular transport
|
(42 genes)
|
ISO
|
|
GO:0070534 [list] [network] protein K63-linked ubiquitination
|
(50 genes)
|
IBA
IMP
|
|
GO:1901016 [list] [network] regulation of potassium ion transmembrane transporter activity
|
(63 genes)
|
ISO
|
|
GO:0051865 [list] [network] protein autoubiquitination
|
(72 genes)
|
ISO
|
|
GO:0032410 [list] [network] negative regulation of transporter activity
|
(87 genes)
|
ISO
|
|
GO:0051224 [list] [network] negative regulation of protein transport
|
(138 genes)
|
ISO
|
|
GO:0043433 [list] [network] negative regulation of DNA-binding transcription factor activity
|
(165 genes)
|
IDA
|
|
GO:0045732 [list] [network] positive regulation of protein catabolic process
|
(221 genes)
|
IBA
|
|
GO:0000209 [list] [network] protein polyubiquitination
|
(225 genes)
|
IBA
|
|
GO:0043161 [list] [network] proteasome-mediated ubiquitin-dependent protein catabolic process
|
(298 genes)
|
IBA
IMP
ISO
|
|
GO:0042391 [list] [network] regulation of membrane potential
|
(462 genes)
|
ISO
|
|
GO:0016567 [list] [network] protein ubiquitination
|
(491 genes)
|
IBA
IDA
ISO
|
|
GO:0034765 [list] [network] regulation of ion transmembrane transport
|
(497 genes)
|
IBA
ISO
|
|
GO:0006511 [list] [network] ubiquitin-dependent protein catabolic process
|
(498 genes)
|
IEA
|
|
GO:0000122 [list] [network] negative regulation of transcription by RNA polymerase II
|
(948 genes)
|
IBA
IDA
ISO
|
|
GO:0010629 [list] [network] negative regulation of gene expression
|
(1078 genes)
|
ISO
|
|
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II
|
(1250 genes)
|
IGI
|
|
GO:0045892 [list] [network] negative regulation of transcription, DNA-templated
|
(1298 genes)
|
IDA
|
|
|
GO CC |
|
GO MF |
GO:0061630 [list] [network] ubiquitin protein ligase activity
|
(308 genes)
|
IBA
IDA
|
|
GO:0061629 [list] [network] RNA polymerase II-specific DNA-binding transcription factor binding
|
(323 genes)
|
IGI
IPI
ISO
|
|
GO:0004842 [list] [network] ubiquitin-protein transferase activity
|
(413 genes)
|
IDA
ISO
|
|
GO:0008134 [list] [network] transcription factor binding
|
(673 genes)
|
ISO
|
|
GO:0016740 [list] [network] transferase activity
|
(2235 genes)
|
IEA
|
|
GO:0005515 [list] [network] protein binding
|
(9507 genes)
|
IPI
|
|
|
KEGG |
mmu04120 [list] [network] Ubiquitin mediated proteolysis (147 genes) |
|
Protein |
NP_080106.1
XP_006531362.1
XP_006531364.1
|
BLAST |
NP_080106.1
XP_006531362.1
XP_006531364.1
|
Orthologous |
[Ortholog page]
WWP1 (hsa)
WWP2 (hsa)
Itch (mmu)
Su(dx) (dme)
ITCH (hsa)
Wwp1 (mmu)
wwp-1 (cel)
Wwp2 (rno)
Wwp1 (rno)
Itch (rno)
WWP2 (gga)
ITCH (gga)
WWP1 (gga)
ITCH (cfa)
WWP2 (cfa)
wwp2 (dre)
WWP1 (mcc)
WWP2 (mcc)
ITCH (mcc)
itchb (dre)
itcha (dre)
WWP1 (cfa)
ITCH (fca)
WWP1 (fca)
WWP2 (fca)
|
Subcellular localization wolf |
mito 4,
nucl 4,
cyto_nucl 3,
cyto 2
|
(predict for NP_080106.1)
|
mito 4,
nucl 4,
cyto_nucl 3,
cyto 2
|
(predict for XP_006531362.1)
|
cyto 5,
cyto_nucl 5,
cyto_pero 3,
nucl 3,
cyto_mito 3,
cyto_plas 3
|
(predict for XP_006531364.1)
|
|
Gene coexpression |
Network*for coexpressed genes |
KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
mmu03040 |
Spliceosome |
3 |
|
Genes directly connected with Wwp2 on the network
coex z* |
Locus |
Function* |
Coexpression detail |
CoexPub |
Entrez Gene ID* |
5.9 |
Xab2 |
XPA binding protein 2 |
[detail] |
0 |
67439 |
5.2 |
Sugp1 |
SURP and G patch domain containing 1 |
[detail] |
0 |
70616 |
5.1 |
Chmp1a |
charged multivesicular body protein 1A |
[detail] |
0 |
234852 |
|
Coexpressed gene list |
[Coexpressed gene list for Wwp2]
|
Gene expression |
All samples |
[Expression pattern for all samples]
|
Tissue specificity* |
|